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慢性阻塞性肺疾病与缺血性卒中

Chronic Obstructive Pulmonary Disease and Ischemic Stroke
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摘要 卒中和慢性阻塞性肺疾病(COPD)在人群当中都是高发疾病,对病人的生活质量造成很大的影响,它们之间是否存在相关性是值得关注的。研究表明COPD是卒中的独立危险因素,主要增加动脉粥样硬化型卒中风险。这与COPD引起的患者发生感染、系统性炎症反应具有相关性,c反应蛋白(CRP)、白介素(IL)-6、IL-8、核转录因子(NF-κB)、肿瘤坏死因子α(TNF-α)均参与了这一过程,系统性炎症通过炎症本身及促进动脉粥样硬化形成增加卒中风险。本文就COPD与卒中的相关性、COPD发生卒中的特点及其原因进行探讨。 Stroke and chronic obstructive pulmonary disease (COPD) are consider as the most common causes of death and persisting disability. Whether there is a relationship between stroke and COPD is worthy of attention. Studies have shown that COPD is an independent risk factor for stroke. This is attributed to increased systemic inflammation. This article reviews the advances and mechanisms of isehemic strokes after COPD.
作者 高宇 黄志亮
出处 《国际老年医学杂志》 2014年第2期91-95,共5页 International Journal of Geriatrics
关键词 COPD 卒中 炎症反应 感染 COPD Stroke Inflammation Infection
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参考文献32

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