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高血压病患者血浆内皮素水平与靶器官损害的关系 被引量:1

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摘要 目的:本研究旨在探讨高血压病患者的血浆内皮素水平与靶器官损害的关系。方法:对104例高血压病患者(一级18例,二级38例,三级48例)和28例健康对照组清晨抽取静脉血,用放射免疫法测定血浆内皮素浓度。结果:正常成人血浆内皮素水平51.92 ±12.54nl/L,高血压病者为74.54±35.05nl/L(P<0.001)。且随着靶器官损害程度加重血浆内皮素水平增高,与高血压分期级别相平行(P<0.01)。其中以脑血管并发症为主者血浆内皮素水平升高最明显(P<0.01)。结论:高血压病时血浆内皮素的合成与释放增加,内皮素参与了高血压的发生、发展及对靶器官损害这一病理过程。
出处 《中原医刊》 2001年第2期1-2,共2页 Central Plains Medical Journal
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