摘要
目的探讨持续非卧床腹膜透析患者低钾血症的临床特征及相关影响因素。方法回顾性分析137例持续非卧床腹膜透析患者的临床资料。结果发生低钾血症37例(27.0%)。低钾组与非低钾组比较,年龄、血钾、血磷、血尿素氮、血清肌酐、血清白蛋白、血浆前白蛋白、血红蛋白及尿素清除率水平差异均有统计学意义(P均<0.05);而血糖、TC、TG、C反应蛋白、血钙、血钠、甲状旁腺素、尿量、超滤量、性别、营养不良发生率及腹膜平衡试验类型差异无统计学意义(P均>0.05)。老年组低钾发生率为41.4%,明显高于非老年组的28.1%(P<0.05)。营养不良组血钾水平低于营养良好组(P<0.05),而低钾患病率高于营养良好组(P<0.05)。血钾与血尿素氮、白蛋白、前白蛋白、血红蛋白、主观综合营养评估法评分、肌酐及血磷呈正相关关系(P<0.05),与年龄、超滤量及尿素清除率呈负相关关系(P<0.05)。结论腹膜透析患者低钾发生率较高。血钾与年龄、营养状态及贫血密切相关,及时纠正低钾血症可以改善患者预后。
Objective To investigate the clinical features of hypokalemia and its related influence factors in patients with continuous ambulatory peritoneal dialysis （CAPD）.Methods A clinical data of 137 patients with CAPD were analyzed retrospectively .Results Hypokalemia occurred in 37 cases（27.0%）.There were significant differences in age,serum potassium,serum phosphorus,blood urea nitrogen（Bun）,serum creatinine（Scr）,serum albumin（ALB）, prealbumin（PA）,hemoglobin （ Hb） and KT/V between hypokalemia and non-hypokalemia groups （ all P〈0.05）. There was no significant difference in serum glucose , total cholesterol （ TC ） , triglyceride （ TG ） , C-reactive protein （CRP）,serum calcium,serum sodium,parathyroid hormone,urine volume,ultrafiltration volume,gender,the incidence of malnutrition and PET type between hypokalemia and non-hypokalemia groups （ all P 〉0.05 ） .The incidence of hypokalemia in senile patients was 41.4%,which was significantly higher than that （28.1%） in non-senile patients （P〈0.05）.The serum level of potassium in malnutrition group was lower than that in good nutrition group （P〈0.05）, while the incidence of hypokalemia in malnutrition group was higher than that in good nutrition group （ P〈0.05） .The level of potassium positive correlated with Bun,ALB,PA,Hb,subjective global assessment（SGA） score,Scr and serum phosphorus （P〈0.05）,but negatively correlated with age ,ultrafiltration volume and KT/V（P〈0.05）.Conclusion A higher incidence of hypokalemia can be observed in CAPD patients .The level of potassium closely correlates with age ,nutri-tional status and anemia .The treatment of hypokalemia in time can improve the prognosis of CAPD patients .
出处
《广西医学》
CAS
2014年第2期204-206,共3页
Guangxi Medical Journal
关键词
腹膜透析
低钾血症
尿毒症
影响因素
相关性
Peritoneal dialysis
Hypokalemia
Uremia
Influence factor
Correlation
