摘要
目的观察格列吡嗪控释片及速释片治疗 2型糖尿病的疗效对照 ,评价格列吡嗪控释片 ,其为依从性良好的抗糖尿病药物。 方法治疗组 2 2例服用控释片 ,对照组 2 0例服用速释片。两组均测试服用前后葡萄糖耐量、胰岛素、C肽及糖化血红蛋白。 结果控释片及速释片均有较好的降糖效果 ,而控释片又不增加血胰岛素及C肽水平。结论控释片降糖作用安全可靠 ,又减少了高胰岛素血症的发生。
Objective To compare the results of controlled-release glipizide and immediate-release glipizide in treating type 2 diabetes mellitus. Methods 22 patients took controlled-release glipi zide as treating group, 20 took immediate-release glipizide as compared. The glucose tolerance, insulin, C-peptide and HbA 1c were measured before and after treatment. Results Both of controlled-release glipizide and immediate-release glipizide had good results for controlling blood sugar, but controlled-release glipizide did not increase insulin and C-peptide level. Conclusion The controlled-release glipizide had safe and reliable results for controlling blood sugar and decreasing insulin resistence.
出处
《上海第二医科大学学报》
CSCD
2001年第1期84-85,共2页
Acta Universitatis Medicinalis Secondae Shanghai
