摘要
目的:对养阴清肺颗粒原质量标准中芍药苷的薄层鉴别方法进行改进,使得处方中玄参与芍药苷的鉴别能在同一条件下同一板中进行鉴别。方法:对原标准中芍药苷的薄层鉴别项下供试品溶液的制备方法进行改进,将提取方法改为用水饱和的正丁醇进行萃取,增加玄参对照药材溶液的制备方法,按原标准中的薄层色谱条件同时鉴别处方中的芍药苷和玄参。结果:改进后薄层色谱方法在同一薄层条件下同时鉴别处方中的芍药苷和玄参,且色谱斑点清晰、无干扰、分离度及重复性好。结论:改进法更有利于控制产品的质量,且简化了操作。
Objective： To improve the TLC identification method in the quality standard for Yangyin Qingfei granules by identifying paeoniflorin and radix scrophulariae on the same condition plate. Methods： The pieparation method for paeoniflorin sample solution in the original standard of TLC identification was improved, the extraction method was water -saturated n -butanol extraction, and the reference crude herb solution of radix scrophulariae was prepared. Simultaneous TLC identification of paeoniflorin and radix scrophulariae was carried out according to the method described in the original standard. Results： The improved TLC method could be used in the simultaneous identification of paeoniflorin and radix scrophulariae, the spots were clear, and the separation and reproducibility were promising without interference. Conclusion： The improved method is more useful in the quality control of the product with simplified operation.
出处
《中国药师》
CAS
2014年第2期335-336,共2页
China Pharmacist
基金
石家庄高端医药产业园区创新药物孵化基地项目(编号:2011ZX09401-306)
关键词
养阴清肺颗粒
芍药苷
玄参
薄层色谱鉴别
Yangyin Qingfei granules
Paeoniflorin
Radix scrophulariae
TLC
