摘要
目的探讨神经外科患者全麻术后恢复期恶心呕吐（PONV）的发生情况及其危险因素。方法择期行神经外科手术的7843例患者进行围术期变量的单因素比较和多因素Logistic回归分析，筛选发生PONV的危险因素。结果1176例患者全麻恢复期发生PONV，发生率为15％。Logistic回归分析提示女性、幕下肿瘤、长时间手术、术后中重度疼痛是发生PONV的危险因素；预防性使用抗呕吐药物、全凭静脉麻醉为保护因素（P〈0．05）。结论神经外科患者女性、幕下肿瘤、长时间手术、术后中重度疼痛是麻醉恢复期PONV的危险因素；预防性使用抗呕吐药物、全凭静脉麻醉可以减少PONV的发生。
Objective To investigate the incidence and risk factors for postoperative nausea and vomiting （PONV） following neurosurgical anesthesia. Methods 7 843 patients undergoing elective neurosurgery were included in this study. Patients＇ perioperative informations were recorded. Univariate and multivariate logistic regression was used to analyze the risk factors for PONV. Results PONV developed in 1 176 patients within 3 h following neurosurgery and the incidence was 15%. The logistic regression analysis indicated that the risk factors for PONV included female sex, infratentorial craniotomy, longer duration of surgery and postoperative median to severe pain. 5 - HT3 receptor antagonists prophylaxis and total intravenous anesthesia （ TIVA ） were protective factors （ P 〈 0. 05 ） . Conclusions Female sex, infratentorial eraniotomy, longer duration of surgery and postoperative median to severe pain were predictors of PONV. 5 - HT3 receptor antagonists prophylaxis or TIVA will decrease the incidence of PONV.
出处
《中华神经外科杂志》
CSCD
北大核心
2014年第2期166-169,共4页
Chinese Journal of Neurosurgery
关键词
术后恶心呕吐
危险因素
神经外科手术
麻醉恢复期
Postoperative nausea and vomiting
Risk factors
Neurosurgical procedures
Anesthesia recovery period
