摘要
目的:探索治疗地震脑损伤认知功能障碍的中西医结合综合康复方案。方法:采用多中心随机对照研究方法,将合格受试者随机分为针刺康复组(38例)和康复组(35例)。针刺康复组给予针刺、高压氧、认知康复训练相结合的中西医结合综合康复方案治疗,康复组给予高压氧、认知康复训练方案治疗,评价其疗效及安全性。结果:①治疗2个月后两组患者智能状态、认知功能、日常生活能力等指标均得到显著改善(均P<0.01)。②在改善程度上,治疗2个月后针刺康复组的智能状态检查量表(MMSE)评分为(24.11±4.08)分,日常生活能力Barthel指数(BI)评分为(75.45±13.95)分,较康复组[(17.05±3.84)分、(66.06±12.75)分]改善更显著(均P<0.01);治疗结束后6个月随访,针刺康复组在认知功能、日常生活能力上的继续改善程度较康复组亦显著(P<0.01,P<0.05)。结论:以针刺、高压氧、认知康复训练相结合的中西医结合综合康复方案治疗地震脑损伤认知功能障碍安全有效,较单纯西医康复方案治疗更具疗效优势。
Objective To explore the comprehensive program of integrated Chinese and western medicine in the treatment of cognitive impairment in earthquake brain injury. Methods The multi-central randomized controlled trial was adopted. The qualified subjects were randomized into an acupuncture＋ rehabilitation group （38 cases） and a rehabilitation group （35 cases）. In the acupuncture ＋ rehabilitation group, acupuncture, hyperbaric oxygen （HBO） and cognitive rehabilitation training were combined as the comprehensive program of integrated Chinese and western medicine in the treatment. In the rehabilitation group, HBO and cognitive rehabilitation training were adopted. The efficacy and safety were assessed. Results （DAfter treatment of 2 months, the intelligent state, cognitive function and activity of daily life of patients were improved in the both groups （all P^0.01）. （~ After treatment of 2 months, the score of MMSE and the score of activity of daily life were （24. 11~4. 08） and （75.45：t= 13.95） in the acupuncture＋rehabilitation group, which were more significant as compared with （17.05±3.84）, （66.06±12.75） in the rehabilitation group, respectively （both P〈0.01）. In 6-month follow-up visit after treatment, the cognitive function and activity of daily life were xmproved continuously in the acupuncture＋ rehabilitation group, which was more significant as compared with the rehabilitation group （P^0.01, P^0.05）. Conclusion The integrated Chinese and western medicine of acupuncture, HBO and cognitive rehabilitation training is safe and effective in the treatment of cognitive impairment in earthquake brain injury. The therapeutic effect is more advantageous as compared with the simple rehabilitation program of western medicine.
出处
《中国针灸》
CAS
CSCD
北大核心
2014年第2期105-109,共5页
Chinese Acupuncture & Moxibustion
基金
国家高技术研究发展计划(国家863计划)项目:2008 AA 022406
关键词
地震脑损伤
认知功能障碍
针刺疗法
康复疗法
综合方案
随机对照研究
earthquake brain injury
cognitive impairment
acupuncture therapy
rehabilitation therapy
comprehensive program
randomized controlled trial （RCT）
