摘要
背景代谢综合征（metabolicsyndrome，MS）是以腹部型肥胖、胰岛素抵抗（insulinresistance，IR）、高血压、脂代谢异常、糖耐量下降或2型糖尿病为主要特征的一种症候群，近年来其发病率呈明显上升趋势。它对机体的心、肺、脑等重要器官都有影响，因此大大增加了麻醉和手术过程的风险。目的回顾近年来国内外关于MS的研究，为MS患者的术前风险评估及麻醉管理提供参考。内容阐述MS的概念、发病机制及流行病学调查，并且从呼吸系统、循环系统、消化系统等方面探讨MS的术前风险评估及麻醉管理。趋向争取早日制定出与MS相适应的麻醉管理策略及临床路径。
Background The metabolic syndrome （MS） is a distinct obesity-related syndrome characterized by truncal obesity, insulin resistance （IR）, dyslipidemia, hypertension and decreased glucose tolerance （or Type 2 diabetes）, of which the prevalence has been increasing obviously in recent years. The MS affects multiple interacting organ systems, and greatly increases the perioperative risks of anesthesia and surgical procedures. Objective The objective of this review was to offer reference for the perioperative risk assessment and the anesthetic management of patients with the MS, by summarizing current opinions and actualities available. Content Elaborating the concept, pathogenesis and epidemiology of the MS, and discussing the perioperative risk assessment and management from different aspects, such as the physiopathologic changes in the respiratory, circulatory, and digestive systems. Trend Our review may help to provide information for the development of anesthetic management strategies and clinical algorithms.
出处
《国际麻醉学与复苏杂志》
CAS
2014年第2期149-153,161,共6页
International Journal of Anesthesiology and Resuscitation
基金
国家自然科学基金（81070880）
关键词
代谢综合征
风险评估
麻醉管理
胰岛素抵抗
肥胖
Metabolic syndrome
Risk assessment
Anethesia management
Insulin resistance
Obesity
