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右美托咪啶或丙泊酚联合瑞芬太尼用于后腹腔镜手术效果比较 被引量:3

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摘要 目的:比较右美托咪啶或丙泊酚联合瑞芬太尼用于后腹腔镜手术效果。方法:将60例ASAⅠ~Ⅱ级后腹腔镜手术的患者随机分为2组,每组30例。D组予盐酸右美托咪啶负荷剂量0.5μg/(kg·h)静脉泵注10 min,术中继续泵注右美托咪啶0.3μg/(kg·h),瑞芬太尼20μg/(kg·h)。 P 组予丙泊酚5 mg/(kg·h)静脉泵注10 min,术中继续以丙泊酚4 mg/(kg·h),瑞芬太尼20μg/(kg·h)微泵维持。观察麻醉诱导前(T0)、气管插管后1 min(T1)、气腹后即刻(T2)、气腹后30 min(T3)、气腹结束时(T4)、拔管后即刻(T5)患者心率(heart rate,HR)、平均动脉压(mean arterial blood pressure,MAP),苏醒时间、镇痛、镇静评分及唤醒期间的呛咳、躁动等相关不良反应。结果:二组比较T0、T5点HR、MAP 差异有统计学意义(均P〈0.05);D组唤醒时间长于P组,但差异无统计学意义(P〉0.05);镇痛评分效果D组明显优于P组(均P〈0.05);苏醒时躁动、呛咳发生率P组高于D组(均P〈0.05);拔管后D 组患者术后镇静优于P组(均P〈0.05)。结论:右美托咪啶联合瑞芬太尼用于后腹腔镜手术,效果优于丙泊酚联合瑞芬太尼。
作者 姚晓平 宋杰
出处 《南通大学学报(医学版)》 2013年第6期569-570,共2页 Journal of Nantong University(Medical sciences)
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