摘要
用小鼠沸腾氨蒸汽引咳和豚鼠枸橼酸喷雾引咳法进行镇咳试验 ,小鼠酚红法和大鼠毛细管法做祛痰试验 ,以及进行整体和离体豚鼠平喘试验。结果表明痰咳清胶囊具有较强的镇咳、祛痰和平喘作用 ,且有明显的时效关系 ,其镇咳和祛痰作用 ,以用药后 1~ 6h最为理想 ;平喘作用则在用药后 1h内发挥最大效果。
Results of experiments such as ammonia steaming test in mice and citric acid test in guinea pigs, phenol red secretion test in mice and capillary expectorant test in rats, in-vivo and in-vitro antiasthmatic tests in guinea pigs proved that Tankeqing capsule had good antitussive, expectorant and antiasthmatic effects and a significant time-effect relationship was showed. The antitussive effect and expectorant effect arrived to the peak in 1-6h after oral administration, and the antiashmatic effect in about 1h.
出处
《中药新药与临床药理》
CAS
CSCD
2001年第1期22-24,共3页
Traditional Chinese Drug Research and Clinical Pharmacology
关键词
痰咳清胶囊
药理学
咳嗽
喘证
中医药疗法
Tankeqing capsule/ pharmacology
cough/TCD therapy
dyspnea-asthma syndrome/ TCD therapy