摘要
目的:观察丁溴东莨菪碱用于宫内节育器取出术的临床疗效及安全性。方法:将86例行宫内节育器取出术患者按随机数字表法分为观察组(48例)和对照组(38例),观察组患者予丁溴东莨菪碱20 mg,肌肉注射30 min后行节育器取出术,对照组患者不予任何药物辅助,常规行节育器取出术。观察两组患者宫颈软化疗效和疼痛疗效和术中出血量及不良反应发生情况。结果:观察组患者宫颈软化疗效、疼痛疗效总有效率显著高于对照组,两组比较差异均有统计学意义(P<0.05);两组患者术中出血量比较差异无统计学意义(P>0.05);除对照组患者出现2例血压下降、头晕、心悸外,其余患者均未见明显不良反应发生。结论:丁溴东莨菪碱用于宫内节育器取出术,疗效显著,安全性较好。
OBJECTIVE： To observe clinical efficacy and security of scopolamine butylbromide in intrauterine devices removal. METHODS： 86 female patients underwent intrauterine devices removal were divided randomly into observation group （48 cases） and control group （38 cases）. Observation group were given intramuscular injection of scopolamine butyl bromide 20 mg firstly, 30 min later received removal of intrauterine devices; control group just received routine intrauterine devices removal and none of drugs. Therapeutic efficacy of cervical softening and pain response, intraoperative blood loss and ADR were observed in 2 groups. RESULTS ： Total effective rate of therapeutic efficacy of cervical softening and pain response in observation group was significantly higher than in control group; there was statistical significance （P〈0.05） ; there was no statistical significance in intraoperative blood loss between 2 groups （P〉0.05） ; there was no obvious ADR in 2 groups during the operation, except dizziness, palpitation and fall of blood pressure. CONCLUSIONS： Scopolamine butylbromide is an effective and safe for intrauterine device removal.
出处
《中国药房》
CAS
CSCD
2014年第8期712-713,共2页
China Pharmacy
关键词
节育器
取出术
丁溴东莨菪碱
疗效
Intrauterine device
Removal of intrauterine device
Scopolamine butylbromide
Therapeutic efficacy
