摘要
目的探析慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)老年患者院内肺部感染的相关危险因素。方法作者医院2011-05/2013-04月院内肺部感染的50例COPD患者为A组,随机抽取同期无肺部感染的50例COPD患者为B组,采用单因素和多因素回归分析危险因素。结果经单因素分析,以下因素与COPD患者院内肺部感染显著相关(P<0.05):合并糖尿病,Ⅱ型呼衰,住ICU时间较长,行机械通气,低蛋白血症,长期应用抗生素和(或)频繁更换,长期使用激素;但经多因素Logistic回归分析发现,仅以下5项因素是COPD患者院内肺部感染的独立危险因素:合并糖尿病,住ICU时间较长,低蛋白血症,长期应用抗生素和(或)频繁更换。结论合并糖尿病,住ICU时间较长,低蛋白血症,长期应用和(或)频繁更换抗生素是老年COPD患者院内肺部感染的独立危险因素,应积极采取治疗措施避免感染发生。
Objective To analyse the related risk factors of nosocomial lung infection of elderly patients with chronic obstructive pulmonary disease （COPD）. Methods A total of 50 patients with nosocomial pulmonary infection of COPD in our hospital from May 2011 to April 2013 were as group A. Another 50 COPD cases without lung infection were as group B. Univariate and multivariate regression analyse was performed to explore the risk factors. Results The Uni- variate analysis indicated the following factors associated with nosocomial lung infection of COPD patients, i. e. diabetes mellitus, type II failure,long stay time in ICU,mechanical ventilation, hypoalbuminemia, long-term use of antibiotics and （or） changed frequently,and long-term use of hormone （P〈0.05）. The multivariate analysis indicated the following five factors as independent risk factors,i, e. diabetes mellitus,long stay time in ICU,hypoalbuminemia,long-term use of antibiotics and （or） changed frequently. Conclusion Diabetes mellitus, ICU time longer, hypoalbuminemia, long-terra use of an- tibiotics and/or frequent replacement are the independent risk factors of elderly COPD patients with lung infection. Measures should be taken to prevent infection.
出处
《华南国防医学杂志》
CAS
2013年第12期891-893,共3页
Military Medical Journal of South China
关键词
慢性阻塞性肺疾病
危险因素
院内肺部感染
Chronic obstructive pulmonary disease
Risk factors
Nosocomial lung infection
