摘要
肥胖是一种慢性营养性疾病,本质是机体的能量代谢平衡发生紊乱,随着人们生活水平的提高和生活方式的改变,肥胖已经成为危害人类健康的第一大杀手。肥胖能诱发一系列慢性代谢疾病,如Ⅱ型糖尿病、高血压、高血脂等。然而市场上化学减肥产品种类泛滥,副作用大,容易反弹,以及市场上对减肥药不可或缺的需求为天然减肥药、中草药等的迅猛发展提供了一定的平台。大部分天然减肥药,中草药减肥活性成分不明确,药理机制不清楚等,是其走向世界的瓶颈,故本文对天然产物、中草药减肥降脂活性成分的作用机理、分类以及分子水平研究动态作系统综述并对其快速发展提出建议。
Obesity is a chronic nutritional disease, and its essence is a disorder of body＇s energy metabolism balance. With the development of people＇s living standard and change of lifestyle, obesity has become a serious danger to the mankind health. Obesity can trigger a series of chronic metabolic diseases, such as II type diabetes, hypertension, hyperlipidemia, etc. However, the chemical products reducing weight have a great variety in the market, side effects and are easy to rebound, in addition to the indispensable needs of weight-loss drugs in market which both provide a platform to develop rapidly for natural medicine and Chinese herbal medicine about reducing weight. But, the active ingredients to reduce weight of most natural medicine and Chinese herbal medicine and the pharmacological mechanism are not clear is the bottleneck to the world. Therefore, this paper reviews the mechanism, classification and molecular level research of active ingredients of natural medicine and Chinese herbal medicine which were researched for weight losing in recent years and also puts forward several opinions to promote its rapid development.
出处
《现代生物医学进展》
CAS
2014年第2期361-363,376,共4页
Progress in Modern Biomedicine
基金
国家自然科学基金项目(81173107)
广东省科技计划项目(2010B090400467)
中山市科技计划项目(2009H017)
广州市科技计划项目(2011J4300064)
关键词
肥胖
减肥
降脂
Obesity
Weight-losing
Lipid-lowering
