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阻塞型睡眠呼吸暂停低通气综合征与2型糖尿病周围神经病变的临床分析 被引量:4

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摘要 目的探讨阻塞型睡眠呼吸暂停低通气综合征(OSAHS)对2型糖尿病患者周围神经病变的影响。方法选择85例2型糖尿病患者行多导睡眠图监测及下肢肌电图检查,根据呼吸暂停低通气指数分为OSAHS组和对照组,对比两组患者周围神经病变情况,分析2型糖尿病周围神经病变与OSAHS的相关性。结果OSAHS组47例,对照组38例。OSAHS组呼吸暂停低通气指数为(44.3±23.4)次/h,明显高于对照组的(2.6±1.5)次/h,平均血氧饱和度及最低血氧饱和度分别为0.917±0.037、0.728±0.101,均低于对照组的0.956±0.016、0.890±0.033,差异均有统计学意义(P〈0.05或〈0.01)。OSAItS组27例(57.4%,27/47)合并周围神经病变,对照组12例(31.6%,12/38)合并周围神经病变,OSAHS组合并周围神经病变发生率明显高于对照组,差异有统计学意义(P〈0.01)。两组胫神经运动神经传导速度比较差异无统计学意义(P〉0.05),OSAHS组腓神经运动神经传导速度、胫神经感觉神经传导速度及腓神经感觉神经传导速度均低于对照组[(44.3±4.1)m/s比(46.7±3.6)m/s、(34.1±5.1)m/s比(37.7±4.2)m/s、(36.2±4.7)m/s比(40.7±3.1)m/s],差异有统计学意义(P〈0.05)。多因素Logistic回归分析结果显示,病程(OR=2.12,95%C1:0.68~5.13,P=0.032)、OSAHS(OR=1.52,95%CI:0.42~4.61,P=0.026)与糖尿病周围神经病变相关。结论OSAHS可能与2型糖尿病患者的周围神经病变相关。
出处 《中国医师进修杂志》 2014年第1期42-44,共3页 Chinese Journal of Postgraduates of Medicine
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