摘要
目的：探讨子宫动脉栓塞治疗子宫腺肌症对月经和卵巢功能的影响。方法：选取45例行子宫动脉栓塞治疗的子宫腺肌症患者作为子宫动脉栓塞组（UAE组），选取同期45例行子宫切除术子宫腺肌症者为子宫切除组（LAVH组），并选取45例正常体检者作为对照组，比较3组患者治疗前后的，FSH及E2值，以及LAVH组和UAE组患者的生活质量，并观察子宫动脉栓塞组的月经情况。结果：术后7天，LAVH组患者的FSH值明显高于术前（P〈0．05），随着时间的增加FSH值呈上升趋势，且明显高于术前（P〈0．01）；而E2值明显低于术前，随着时间的增加其值呈下降趋势，且明显低于术前（P〈0．01）。术后1年和3年LAVH组的FSH值明显高于UAE组（P〈0．01），E2值明显低于UAE组（P〈0．01）。术后3个月，UAE组患者43例月经改善，占总数的95．56％，所有患者均在3～4个月经周期内，月经恢复正常，所有患者均于术后5～6个月痛经完全消失，贫血状况均得到改善。UAE组患者术后1年的生理领域、心理领域、社会领域以及主观领域分值明显高于LAVH组，术后3年UAE组患者的生活质量的各项指标均优于LAVH组（P〈0．05或P〈0．01）。结论：子宫动脉栓塞治疗能改善子宫腺肌症患者的月经和卵巢功能，提高生活质量，值得在临床广泛推广。
Objective： To discuss the effect of uterine artery embolization （UAE） for the treatment of adenomyosis on menstruation and ovarian function. Methods： 45 cases with adenomyosis who performed uterine artery embolization were chosen as UAE group, 45 cases who performed hysterectomy in the same period were chosen as LAVH group, while 45 health people were chosen as control group. FSH and E2 value before and after treatment were observed and compared in three groups. The quality of life in LAVH group and UAE group were com- pared, and the menstrual conditions of UAE group was observed. Results： FSH value of LAVH group in 7 d after operation was obviously higher than that before operation （ P 〈 0. 05 ） , it showed an increasing tendency with the increasing of time and it obviously higher than that before operation （ P 〈 0. 01 ） . While E2 value was obviously lower than that before operation, it showed an decreasing tendency with the in- creasing of time and it obviously lower than that before operation （ P 〈 0. 01 ） . FSH value in LAVH group was obviously higher than that in UAE group after 1 year and 3 years （ P 〈 0. 01 ）, while E2 value was obviously lower than that in UAE group （ P 〈 0. 01 ） . Menstruation of 43 cases （95.56%） in UAE group was improved after 3 months. All the cases menstrual cycle and period returned to normal after 3 - 4 months, dysmenorrhea completely disappeared after 5 - 6 months, and anemia was improved. The values of UAE group in physiological, psychological, social and subjective field were obviously higher than those in LAVH group after 1 year. Each index of living quality in UAE group were superior to those in LAVH group after 3 years （P 〈 0. 05 or 0. 01 ） . Conclusion： Uterine artery embolization can improve men- struation and ovarian function of adenomyosis patients, and thus can improve their quality of life. It is worth spreading in clinic.
出处
《中国妇幼保健》
CAS
北大核心
2014年第4期512-515,共4页
Maternal and Child Health Care of China
基金
海南省自然科学基金立项项目〔812178〕
关键词
子宫动脉栓塞
子宫腺肌症
月经
卵巢功能
Uterine artery embolization
Adenomyosis
Menstruayion
Ovarian function
