摘要
目的:观察孟鲁司特钠与美敏伪麻液联合治疗上气道咳嗽综合征的疗效。方法:将239例上气道咳嗽综合征患者随机分为治疗组与对照组,治疗组患者口服孟鲁司特钠(10 mg,qn,5 d)与美敏伪麻液(10 ml,tid,5 d),对照组患者口服孟鲁司特钠(10mg,qn,5 d)与复方甘草口服液(10 ml,tid,5 d),根据咳嗽症状评分评价临床疗效。结果:治疗前,治疗组与对照组患者的咳嗽症状评分分别为1.99±0.58和1.99±0.61(P>0.05);治疗后,治疗组与对照组患者的咳嗽症状评分分别为0.31±0.23和1.21±0.63(P<0.05);治疗组与对照组的总有效率分别为92.44%、60.83%(P<0.05)。结论:孟鲁司特钠与美敏伪麻液联合治疗上气道咳嗽综合征效果好,可在临床推广。
OBJECTIVE ： To observe the clinical efficacy of montelukast sodium and Pseudoephedrine hydrochloride solution on upper airway cough syndrome （UACS）. METHODS： 239 UACS patients were randomized into treatment group and control group. Treatment group was given montelukast sodium （10 rag, qn, 5 d） and Pseudoephedrine hydrochloride solution （10 ml, tid, 5 d） oral ly; control group was given montelukast sodium （10 mg, qn, 5 d） and Compound glycyrrhiza oral solution （10 ml, tid, 5 d）. Clini cal efficacies were evaluated according to cough scores. RESULTS ： Before treatment, the cough scores of treatment group and con trol group were 1.99 ± 0.58 and 1.99±0.61（P〉0.05） ; the cough scores of 2 groups after treatment were 0.31 ± 0.23 and 1.21± 0.63 （P〈0.05）. Total clinical efficacies of both groups were 92.44% and 60.83% （P〈0.05）. CONCLUSIONS： The clinical efficacy of montelukast sodium and Pseudoephedrine hydrochloride solution on UACS is sound and can be recommended clinically.
出处
《中国药房》
CAS
CSCD
2014年第6期541-543,共3页
China Pharmacy
关键词
孟鲁司特钠
美敏伪麻液
上气道咳嗽综合征
Montelukast sodium
Pseudoephedrine hydrochloride solution
Upper airway cough syndrome
