摘要
采用天然交联剂京尼平,结合相分离技术与冷冻干燥方法,制备不同交联度的明胶多孔支架。结果表明,支架的交联度随着京尼平浓度的增加而升高,最高可以达到65.3%;不同交联度的明胶支架微观呈相互连通的多孔结构,且孔径随交联度的升高而降低;通过调控明胶支架的交联度。
Genipin crosslinked gelatin scaffolds with different crosslinking separation technique and a freeze-drying method. The results indicated the c degrees were thbricated using phase rosslinking degrees were increased to 65.3% when the concentration of genipin was 20mg/mL. The scaffold displayed high interconnected porous micro- structure and the pore size was decreased at a low crosslinking degree. In vitro degradation test showed the tion rate was controlled by crosslinking degree of gelatin scaffold. degrada
出处
《合成材料老化与应用》
2013年第6期5-7,共3页
Synthetic Materials Aging and Application
基金
国家自然科学基金项目(50872099)
广州市博士后科研启动项目(Q071)
关键词
明胶
京尼平
多孔支架
降解
gelatin, genipin, scaffold, degradation
