摘要
目的 观察支气管扩张并大咯血应用酚妥拉明联合垂体后叶素治疗的临床疗效.方法 选取我院2009年5月~2013年2月收治的90例支气管扩张并大咯血患者作为研究对象,按照随机数字表法随机分为治疗组30例与对照组60例,分别给予酚妥拉明＋垂体后叶素和垂体后叶素治疗,比较两组患者临床疗效.结果 治疗组治疗总有效率高于对照组,但无明显差异（2=2.265,P〉0.05）,治疗组显效率显著高于对照组（=11.054,P〈0.01）,具有统计学差异.治疗组治疗2h完全止血6例,4 h完全止血15例,8 h完全止血8例,8 h后止血率为96.7%;对照组治疗2 h完全止血9例,4 h完全止血18例,8 h完全止血23例,8 h后止血率为83.3%.治疗组8 h止血率显著高于对照组（2=8.236,P〈0.01）.结论 酚妥拉明联合垂体后叶素治疗支气管扩张并大咯血止血效果佳,但应用过程中应注意相关不良反应情况,做好各项监测工作.
Objective To observe the clinical effect of phentolamine combined with pituitrin in the treatment of bronchiectasis patients complicated with hemoptysis. Methods 90 bronehiectasis patients complicated with mas- sive hemoptysis were randomly divided into the treatment group with 30 cases and the control group with 60 cases. They were respectively treated with phentolamine and pituitrin and vasopressin, and then their clinical effect was com- pared. Results The total effective rate was slightly higher in the observation group than in the control group without statistical significance （ ~2 = 2. 265, P 〉 0.05 ）. In the treatment group, 6 cases stopped bleeding 2 hours after the treatment, 15 cases stopped bleeding 4 hours after the treatment, and 8 cases stopped bleeding 8 hours after the treat- ment. The total hemostasis rate of 8 hours after the treatment was 96. 7%, which was obviously higher than that in the control group （83.3%）. Conclusion Phentolamine combined with pituitrin has good curative effect in the treatment of bronchiectasis patients complicated with hemoptysis, but the related adverse reactions in the application process should be paid more attention.
出处
《临床肺科杂志》
2014年第2期303-305,共3页
Journal of Clinical Pulmonary Medicine
