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右美托咪定对老年结肠癌根治术患者术后谵妄的影响 被引量:20

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摘要 术后谵妄(postoperative delirium,POD)是一种急性暂时性神经功能紊乱状态,伴有明显的认知功能障碍、意识水平下降、睡眠-觉醒周期紊乱.老年患者接受大型腹部手术的术后谵妄发生率在10%-40%,谵妄的发病率是预测更长住院时间和更多住院费用的重要指标.右美托咪定是高选择性的α2 肾上腺素受体激动剂,具有镇静、镇痛、抗交感,减少应激反应,稳定血流动力学的作用,还有神经保护作用[1].但右美托咪定对术后谵妄的影响尚存在争议[2].本研究拟探讨在老年患者结肠癌根治术中和术后辅助应用右美托咪定对术后谵妄的影响,评价其防治老年患者术后谵妄的有效性和安全性.……
出处 《中国实验诊断学》 2014年第1期135-137,共3页 Chinese Journal of Laboratory Diagnosis
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