期刊文献+

老年痴呆症的早期预防研究进展 被引量:7

下载PDF
导出
摘要 老年痴呆症严重影响个人记忆,思维和推理能力。随着疾病的进展,让患者很难处理日常生活而失去自理能力,给社会及家庭带来沉重负担。本文目的是通过早期发现,并采取预治措施来延缓病程,从而减轻疾病给家庭及社会带来的压力,提高患者生存质量。
出处 《中国疗养医学》 2014年第1期14-15,共2页 Chinese Journal of Convalescent Medicine
  • 相关文献

参考文献18

  • 1Devanand DP,Pradhaban G,Liu X. Hippocampal and entorhinal atrophy in mild cognitive impairment:prediction of Alzheimer disease[J].{H}NEUROLOGY,2007,(11):828-836. 被引量:1
  • 2Ito N. Clinical aspects of dementia[J].{H}Hokkaido Igaku Zasshi Hokkaido Journal of Medical Science,1996,(03):315-320. 被引量:1
  • 3Tombaugh TN,McIntyre NJ. The mini-mental state examination:a comprehensive review[J].{H}Journal of the American Geriatrics Society,1992,(09):922-935. 被引量:1
  • 4De Meyer G,Shapiro F,Vanderstichele H. Diagnosis-Independent Alzheimer Disease Biomarker Signature in Cognitively Normal Elderly People[J].{H}Archives of Neurology,2010,(08):949-956. 被引量:1
  • 5Singh V,Chertkow H,Lerch JP,er al. Spatial patterns of cortical thinning in mild cognitive impairment and Alzheimer's disease[J].{H}BRAIN,2006,(11):2885-2893. 被引量:1
  • 6许松云,单守勤,冯玉奎,董洪强,姜涛,于庆潭.阿尔茨海默病的影像学诊断现状进展[J].中国疗养医学,2012,21(12):1104-1106. 被引量:1
  • 7Jack CR,Shiung MM,Weigand SD. Brain atrophy rates predict subsequent clinical conversion in normal elderly and amnestic MCI[J].{H}NEUROLOGY,2005,(08):1227-1231. 被引量:1
  • 8石庆丽,韩利坤,袁春,张玉梅.阿尔茨海默病的影像学研究进展[J].中国康复理论与实践,2013,19(4):354-359. 被引量:6
  • 9Den Heijer T,Geerlings MI,Hoebeek FE. Use of hippocampal and amygdalar volumes on magnetic resonance imaging to predict dementia in cognitively intact elderly people[J].{H}Archives of General Psychiatry,2006,(01):57-62. 被引量:1
  • 10Bozzali M,Filippi M,Magnani G. The contribution of voxel-based morphometry in staging patients with mild cognitive impairment[J].{H}NEUROLOGY,2006,(03):453-460. 被引量:1

二级参考文献128

  • 1马波,张建军.与阿尔茨海默病密切相关的α-,β-和γ-分泌酶的研究进展[J].国外医学(药学分册),2005,32(1):22-26. 被引量:6
  • 2李德鹏,马云川,刘力.PET显像在阿尔茨海默病(AD)诊断与研究中的应用[J].CT理论与应用研究(中英文),2006,15(1):1-5. 被引量:8
  • 3Price DL,Tanzi RE,Borchelt DR,et al.Alzheimer's disease:genetic studies and transgenic models[J].Annu Rev Genet,1998,32:461-493. 被引量:1
  • 4Halliday G,Robinson SR,Shepherd C,et al.Alzheimer's disease and inflammation:a review of cellular and therapeutic mechanisms[J].Clin Exp Pharmacol Physiol,2000,27(1-2):1-8. 被引量:1
  • 5Breitner JC.NSAIDs and Alzheimer's disease:how far to generalise from trials[J].Lancet Neurol,2003,2(9):527-527. 被引量:1
  • 6Lim GP,Yang F,Chu T,et al.Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease[J].J Neurosci,2000,20(15):5709-5714. 被引量:1
  • 7TangYP,Haslam SZ,Conrad SE,et al.Estrogen increases brain expression of the mRNA encoding transthyretin,an amyloid beta scavenger protein[J].J Alzheimers Dis,2004,6(4):413-420. 被引量:1
  • 8Morgan D,Gordon MN,Tan J,et al.Dynamic complexity of the microglial activation response in transgenic models of amyloid deposition:implications for Alzheimer therapeutics[J].J Neuropathol Exp Neurol,2005,64(9):743-753. 被引量:1
  • 9Teeling JL,Perry VH.Systemic infection and in flammation in acute CNS injury and chronic neurodegeneration:underlying mechanisms[J].Neuroscience,2009,158(3):1062-1073. 被引量:1
  • 10Sheng JG,Zhu SG,Jones RA,et al.Interleukin-1 promotes expression and phosphorylation of neurofilament and tau proteins in vivo[J].Exp Neurol,2000,163(2):388-391. 被引量:1

共引文献16

同被引文献107

  • 1李修英,潘雨利,邵立平,高怡红.离退休老干部老年痴呆症患病情况及相关影响因素[J].中国老年学杂志,2014,34(12):3413-3416. 被引量:12
  • 2郁向静,何俊民.β淀粉样蛋白在阿尔茨海默病中的病因学作用[J].广州医药,2007,38(2):7-10. 被引量:5
  • 3陈国华,单萍,邱昕.黄连解毒汤治疗老年性痴呆(心肝火旺型)临床研究[J].中国中医急症,2007,16(4):386-387. 被引量:41
  • 4Mega MS,Cummings JL,Fiorello T,et al.The spectrum of behavioral changes in Alzheimer's disease[J].Neurology,1996;46(1):130-5. 被引量:1
  • 5Frstl H,Kurz A.Clinical features of Alzheimer's disease[J].Eur Arch Psychiatry Clin Neurosci,1999;249(6):288-90. 被引量:1
  • 6Sharma AK,Kim J,Prior JT,et al.Small bifunctional chelators that do not disaggregate amyloidβfibrils exhibit reduced cellular toxicity[J].Inorg Chem,2014;53(21):11367-76. 被引量:1
  • 7Lee JH,Kahn A,Cheng R,et al.Disease-related mutations among Caribbean Hispanics with familial dementia[J].Mol Genet Genomic Med,2014;2(5):430-7. 被引量:1
  • 8Lewis BP,Burge CB,Bartel DP.Conserved seed pairing,often flanked by adenosines,indicates that thousands of human genes are microRNA targets[J].Cell,2005;120(1):15-20. 被引量:1
  • 9Long JM,Ray B,Lahiri DK.MicroRNA-153 physiologically inhibits expression of amyloid-βprecursor protein in cultured human fetal brain cells and is dysregulated in a subset of Alzheimer disease patients[J].J Biol Chem,2012;287(37):31298-310. 被引量:1
  • 10Long JM,Lahiri DK.MicroRNA-101 downregulates Alzheimer's amyloid-βprecursor protein levels in human cell cultures and is differentially expressed[J].Biochem Biophys Res Commun,2011;404(4):889-95. 被引量:1

引证文献7

二级引证文献84

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部