摘要
目的探讨糖尿病合并反杓型高血压的心率变异性(HRV)的临床意义。方法应用动态血压检测糖尿病合并高血压患者,按夜间血压下降率是否超过10%分为杓型高血压组和非杓型高血压组,每组61例,所有入组患者进行动态心电图监测。比较两组HRV时域指标。结果杓型高血压组HRV时域指标明显低于非杓型高血压组(P<0.001)。杓型高血压组HRV指标24h全程全部窦性R-R间期的标准差(SDNN)在不同降低程度(SDNN≤50ms、100ms>SDNN>50ms)的发生率明显高于非杓型高血压组(P<0.001)。结论糖尿病合并反杓型高血压患者心率变异性时域指标降低更明显,提示自主神经损害严重,迷走神经张力降低,交感神经兴奋性增高,预示心血管事件中猝死风险增加。
Objective To investigate the HRV in diabetes mellitus with anti - dipper hypertension and its clinical significance. Methods Dynamic blood pressure monitoring was applied for patients with diabetes mellitus and hypertension. According to the nocturnal blood pressure decline was more than 10 % as dipper hypertension, all patients were divided into dipper group （group A,n= 61） and non- dipper group （group B,n 61）. Dynamic electrocardiograms were detected in all patients. HRV time domine index,inclu- ding SDNN, SDANN, RMSSD and PNN50 in two groups were compared. Results HRV time domine index in A group was lower than that in group B（P〈0. 001）. SDNN in group A incidence was significantly higher than that in group B（P〈0. 001 ）. Conclusion The lower HRV time domine in diabetes mellitus with anti - dipper hypertension suggested that the autonomic nervous system was serious damaged,vagal tone was reduced,sympathetic activity was increased, sudden death risk was increased.
出处
《中西医结合心脑血管病杂志》
2013年第12期1415-1416,共2页
Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
关键词
糖尿病
反杓型高血压
心率变异性
自主神经
diabetes mellitus
anti - dipper hypertension
heart rate variability
autonomic nervous
