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上消化道出血合并急性冠状动脉综合征18例临床分析 被引量:4

Clinical analysis of upper gastrointestinal bleeding complicated with acute coronary syndrome in 18 cases
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摘要 目的探讨上消化道出血(UGIB)并发急性冠状动脉综合征(ACS)的可能原因及有效救治方法。方法回顾性研究某院2008年4月~2013年4月收治的UGIB合并ACS18例患者的临床资料,分析总结该病的临床特点及治疗方法。结果18例患者年龄58~93岁,平均(69.2±10.9)岁,发病以老年男性为主。口服抗血小板药物者15例(83.33%)。严密监护、积极输血、急诊内镜检查及镜下止血治疗是治疗的主要方法,胃镜下止血成功14例(77.80%),病死3例(16.67%)。结论严密监护、积极输血、24h内急诊胃镜检查及镜下止血治疗是UGIB并发ACS救治成功的关键。需要长期口服抗血小板药物的患者,质子泵抑制药可降低消化道出血的发生率,改善预后。 Objective To explore the reason and the effective treatment for upper gastrointestinal bleeding (UGIB) complicated with acute coronary syndrome (ACS). Methods From April 2008 to April 2013 ,the clinical data of 18 patients presented with UGIB and ACS in our hospital were studied retrospectively. The clinical features and the therapeutic procedures were analyzed. Results The age of the patients was from 58 to 93 years with a mean of 69 years. Antiplatelet medications were taken in 15 patients (83.33%). The main treatment included intensive care,blood transfusion,emergency endoscopy and endoscopic hemostasis. The num- ber of patients which were successfully endoscopic hemostasis was 16 (87.56%). Three (16.67%) patients died. Conclusion Inten- sive care, blood transfusion,emergency endoscopy within 24 hours and endoscopic hemostasis were crucial for the treatment of UGIB complicated with ACS. Proton pump inhibitor could reduce the incidence of gastrointestinal bleeding and improved prognosis for pa- tients requiting long-term antiplatelet therapy.
出处 《中华保健医学杂志》 2013年第6期472-474,共3页 Chinese Journal of Health Care and Medicine
关键词 消化道出血 急性冠状动脉综合征 质子泵抑制药 消化内镜 Gastrointestinal bleeding Acute coronary syndrome Proton pump inhibitor Endoscopy
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  • 1Manguso F,Riccio E,Bennato R,et al. In-hospital mortality 111non-variceal upper gastroint estinal bleeding Forrest 1 patiettts[J]. Scand J Gastroenterol,2008,43(12): 1432-1441. 被引量:1
  • 2Tang EW,Wong CK,Herbison P. Global Registry of Acute Coro-nary Events (GRACE) hospi tal discharge risk score accuratelypredicts long term mortality post acute coronary syndrome [J].American Heart Journal, 2007 f 153(1) : 29-35. 被引量:1
  • 3Rao SV,O'Grady K,Pieper KS,et aL Impact of bleeding severityon clinical outcomes among patients with acute cotonary syn-dromes [J]. Am J Cardiol,2005,96(9): 1200-1206. 被引量:1
  • 4Ibanez L,Vidal X,Vendrell L,et al. Upper gastrointestinal ulcerrelapse after initial healing [J]. Aliment Phartnacol Ther,2006,23(4):235-243. 被引量:1
  • 5Kelly JP,Kaufman DW,Jurgelon JM,et al. Risk of aspirin^asso-ciated major upper-gastrointestinal bleeding with enteric-coatedor buffered product[J]. Lancet, 1996,348(23) : 1413-1416. 被引量:1
  • 6Barkun A,Sabbah S,Enns R,et al. The Canadian Registry onNonvariceal Upper Gastrointes tinal Bleeding and Endoscopy(RUGBE) : Endoscopic hemostasis and proton pump inhibitionafe associated with improved outcomes in a real -lif e setting[J]. Am J Gastroenterol,2004, 99(7); 1238-1246. 被引量:1
  • 7Mumtaz K,Ismail FWJafri W,et al. Safety and utility ofoesophago -gastro -duodenoscopy in acute myocardial infarction[J]. European Journal of Gastroenterology & Hepatology,2008,20(1):51-55. 被引量:1
  • 8抗血小板治疗中国专家共识[J].中华心血管病杂志,2013,41(3):183-194. 被引量:244
  • 9Lanas A,Garcia-Rodriguez LA,Arroyo MT,et al. Effect of anti-secrotury drugs and nitrates on the risk of ulcer bleeding associ-ated with nonsteroidal anti -inflammatory drugs, antiplatelat a-gents,and anticoagulants[J]. Am J Gastroenterol,2007,102(3):507-515. 被引量:1
  • 10Chin MW,Yong G,Bulsara MK,et al. Predictive and protectivefactors associated with upper gastrointestinal bleeding after per-cutaneous coronary intervention: a case-control study [J]. Am JGastroenterol,2007,102(11) :2411-2416. 被引量:1

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