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脑梗死患者血清α-羟丁酸脱氢酶(HBDH)的测定及临床意义 被引量:1

Significance of changes of α-HBDH in patients with acute cerebral infarction
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摘要 目的:探讨急性脑梗死患者血清α—HBDH酶活性变化和临床意义。方法:对40例脑梗死急性期、恢复期血清α—HBDH酶检测,同时设立38例正常对照组。结果:(1)40例肌钙蛋白T(cTnT)正常的脑梗死患者平均血清α—HBDH值明显高于正常对照组(P<0.01);(2)大面积脑梗死组α—HBDH值明显高于腔隙性脑梗死组(P<0.01);(3)脑梗死恢复期血清α—HBDH值明显低于急性期(P<0.05)。结论:α—HBDH可用来判断脑梗死后是否有新的梗死或梗死面积是否扩大及病情好转与否的一个有效参考指标。 Objective:To investigate the roles of α-HBDH in acute cerebral infarction .Methods:The serum concentrations of α-HBDH were measured in the acute and recovered stage in 40 cerebral infarction patients ,38 healthy control groups .Results:①The serum levels ofα-HBDH in cerebral infarction groups which the cTnT in normal were significantly higher than those in healthy control groups ( P〈0.01);②The serum levels of α-HBDH in cerebral infarction groups of huge areas were significantly higher than those in lacunar in -farct groups(P〈0.01);③The serum levels of α-HBDH in the recovered stage of cerebral infarction were significantly lower than those in acute stage(P〈0.05).Conclusion:The serum of α-HBDH should be a effective reference index in jndging the areas of infarction whether to expand or have new infarction;as well as the levels of α-HBDH might be a effective index in judging whether the cerebral in-farction patient is recovering or not .
出处 《中国伤残医学》 2014年第2期17-18,共2页 Chinese Journal of Trauma and Disability Medicine
关键词 脑梗死 Α-HBDH Cerebral infarction α-HBDH
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