摘要
为了探讨仙人掌总黄酮对小鼠的抗急性炎症作用。采用耳肿胀法、毛细血管通透性增加、足肿胀法对仙人掌总黄酮的抗急性炎症作用进行研究。结果表明：仙人掌总黄酮各剂量组小鼠耳肿胀度与空白对照组相比差异极显著（P〈0．01）；毛细血管通透性增加实验中，各剂量组的OD值与空白对照组相比差异极限著（P〈0．01）；足肿胀实验中各剂量组0．5～2h肿胀度与空白对照组相比差异极限著（P〈0．01），但各剂量组3h足趾肿胀度与空白对照组无显著差异。仙人掌总黄酮对肿胀反应及毛细血管通透性增加有显著的抑制作用，可减轻肿胀和渗出等局部炎症反应，具有一定的抗急性炎症作用。
The purpose of this study is to evaluate the anti-acute inflammation effect on total flavonoids from opuntia in mice. The ear edema method, increase of capillary permeability and paw edema method were used to study the anti-acute inflammation effect on flavonoid from opuntia in mice. The results showed that the ear swelling degree in every dose group mice was significantly different compared to control mice （/9〈0.01）. The OD values in every dose group mice was significantly different from control mice in the experiment of increase of capillary permeability （P〈0.01）. The paw swelling degree at 0.5-2 h in every dose group mice was significantly different compared to control mice in the experiment of paw edema （P〈0.01）. But the paw swelling degree at 3 h was not significantly different from control group. In conclusion, opuntia total flavonoids has great inhibition on swelling reaction and increase of capillary permeability. It has the effect of deturgescence and exudation in the local inflammatory reaction, presenting anti-acute inflammation effect.
出处
《中国农学通报》
CSCD
2013年第36期400-403,共4页
Chinese Agricultural Science Bulletin
基金
新疆维吾尔自治区重点学科食品科学青年教师科研启动项目"HPLC法分离仙人掌总黄酮及其对急性炎症的影响"
关键词
仙人掌
总黄酮
急性炎症
opuntia
total flavonoids
acute inflammation
