摘要
目的为了解长白山地区正常人群蜱媒传染病的感染状况。方法采集长白山部分地区正常人血清629份,应用间接免疫荧光试验检测5种蜱传病原体的血清抗体,应用SPSS软件进行χ2检验,P<0.05为差异有统计学意义。结果调查地区人群5种蜱传病原体的感染普遍,抗体阳性率分别为斑点热立克次体11.92%、莱姆病螺旋体7.15%、贝氏柯克斯体7.14%、森林脑炎病毒4.45%、查菲埃立克体3.18%,斑点热立克次体明显高于其他4种病原体(χ2=13.431,P<0.01),莱姆病螺旋体和贝氏柯克斯体高于蜱传脑炎病毒和查菲埃立克体(χ2=11.061,P<0.05)。阳性率分布的比较,长白山脉北部、中部地区的6市县阳性率有差别,但无统计学意义(χ2=8.759,P>0.05),珲春地区明显高于南部地区桓仁(χ2=11.579,P<0.01)。调查地区存在西伯利亚和黑龙江立克次体感染,黑龙江立克次体阳性率(9.1%)明显高于西伯利亚立克次体(2.4%),差异有统计学意义(χ2=11.267,P<0.01)。结论长白山地区人群5种蜱媒传染病感染普遍。提示调查地区存在其自然疫源地,应积极做好蜱媒传染病防治及蜱叮咬的防护工作。
Objective To understand the current status of tick-borne infectious diseases infection among residents in Changbai mountainous region. Methods A total of 629blood samples were collected from residents in 7different geographic regions around Changbai mountainous area and were tested by immunofluorescence assays（IFA）for serum antibodies against 5tick-borne infectious diseases pathogens.Chi-square test was used for data analysis. Results The positive rates of antibodies was 11.92%for Spotted fever rickettsias,7.15%for B.burgdorf eri sensu lato, 7.14%for Coxiella burnetii,4.45%for Tick borne encephalitis virus and 3.18%for Ehrlichia chaffeensis.In terms of geographic distribution,the positive rate in Huichun of north area was much higher than that in Huanren of south area（χ2=11.579,P〈0.01）.Also,the antibody positive rate of R.heilongjiangensis was found to be higher than that of R.sibirica（χ2=11.267,P〈0.01）. Conclusions The prevalence of 5tick-borne infectious diseases is high,indicating this mountainous area is the major natural foci.
出处
《中国预防医学杂志》
CAS
2013年第12期886-888,共3页
Chinese Preventive Medicine
基金
辽宁省自然科学基金课题(20092204)
总部基金面上项目(M173)
关键词
蜱媒传染病
血清学调查
间接免疫荧光试验
Tick-borne infectious diseases
Antibody
Immunofluorescence assays
