摘要
目的 :探讨急性白血病 (AL )患者血浆可溶性肿瘤坏死因子受体 (s TNFα R)变化及其意义。方法 :采用放射免疫沉淀—聚乙二醇分析法测定了 2 7例 AL患者血浆 s TNFα R水平 ,并以 15例正常人作对照。结果 :AL患者血浆 s TNFα R水平显著升高 ,与正常对照组差异有显著性 (P<0 .0 1)。结论 :s TNFα R的异常分泌可能是导致
Objective:To appraise the changes of plasma levels of soluble tumor necrosis factor α receptor (sTNFα R)and its clinical significance in patients of acute leukemia(AL).Methods: Plasmas levels of sTNFα R were detected with radioimmuno precipitation polyethylene glycol assay in 27 AL patients,and 15 normal subjects were used as controls.Results:The plasma levels of sTNFα R in AL patients were obviously increased,showing significantly difference compared with normal controls.Conclusion: The abnormal secretion of sTNFα R maybe one importante factor leading to Al cells grow.
出处
《白血病》
2000年第5期274-276,共3页
关键词
急性白血病
肿瘤坏死因子
受体
放射免疫法
Acute leukemia
Soluble tumor necrosis factor α receptor
Radioimmuno precipitation polyethylene glycol assay
