期刊文献+

雷替曲塞联合伊立替康三线治疗晚期结直肠癌疗效及安全性分析 被引量:6

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摘要 雷替曲塞(RTX)是一种喹唑啉叶酸类似物,与5-Fu有相似的抗肿瘤作用,通过抑制胸苷酸合成酶(砖),从而抑制肿瘤细胞的生长,临床上主要用于晚期结直肠癌(CRC)的治疗。
出处 《实用临床医药杂志》 CAS 2013年第24期111-112,共2页 Journal of Clinical Medicine in Practice
基金 中国高校医学期刊临床专项资金(11321174)
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同被引文献94

  • 1岳顺,张大红,周磊磊.雷替曲塞联合多西他赛治疗晚期胃癌的临床疗效[J].肿瘤防治研究,2014,41(2):160-162. 被引量:21
  • 2吴建兵,王汉姣,王顺金,李凌,冯龙.雷替曲塞联合L-OHP与5-Fu/LV联合L-OHP方案治疗晚期结直肠癌的临床疗效比较[J].肿瘤防治研究,2007,34(9):711-713. 被引量:14
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  • 7CunninghamD, ZalcbergJR, Rathll, et al. Final results of a randomized trial comparing'Tomudex' (raltitrexed) with 5-fluorouraeil plus leucovorin in advanced colorectal cancer [J]. Ann Oneol, 1996, 7(9): 961-965. 被引量:1
  • 8Vieitez J M, ValladaresM, PelaezI, et al. A randomized phase II study of raltitrexed and gefitinib versus raltitrexed alone as second line chemotherapy in patients with colorectal cancer[J]. Invest New Drugs, 2011, 29(5): 1038-1044. 被引量:1
  • 9Vyzula R, Kocakova I, Demlova R, et al. Rltitrexed plus oxaliplatin in the second-line treatment of metastatic colorectal cancer [J]. Neoplasma, 2006, 53(2): 119-127. 被引量:1
  • 10Comella P, Casaretti R, Cmcitta E. Oxaliplatin plus raltitrexed and 5-fuorouracil I,v. bolus:a salvage regimen for colorectal Cancer patients[J]. Br J Cancer, 2002, 86(12): 1871-1875. 被引量:1

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