摘要
目的观察子宫内膜异位症术后置左炔诺孕酮宫内节育器的临床疗效。方法选择经手术和病理确诊的子宫内膜异位症患者84例，均行腹腔镜手术，按随机数字表法分为对照组和治疗组，每组42例。对照组术后仅予短期药物治疗，治疗组在对照组治疗的基础上术后放置左炔诺孕酮宫内节育器。术后随访1年，比较两组疗效。结果治疗组随访1年时的疼痛评分为0分，低于对照组的（1．5±0．2）分，差异有统计学意义（P〈0．05）；治疗组术后术后月经量占术前的比例及癌抗原125水平明显低于对照组[（11±3）％比（45±6）％、（7．01±2．97）U／L比（38．79±31．43）U／L]，差异有统计学意义（P〈0．05）；治疗组术后病灶复发率为2．38％（1／42），低于对照组的28．57％（12／42），差异有统计学意义（P〈0．05）。结论子宫内膜异位症术后置左炔诺孕酮宫内节育器能明显缓解患者术后疼痛，减少月经量，降低病灶复发率，临床疗效显著。
Objective To observe the clinical efficacy of levonorgestrel intrauterine device （IUD） on endometriosis patients after surgery. Methods Eighty-four endometriosis patients diagnosed by pathological and surgery were divided into control group and treatment group by random digits table with 42 cases each group. The control group was accepted only short-term drug treatment,while the treatment group was placed levonorgestrel intrauterine device on the basis of control group, then comparing the efficacy after followed up for one year. Results The mean pain score of treatment group was 0, control group was （ 1.5 ± 0.2 ） points, the difference was statistically significant （P 〈 0.05 ）. The menstrual blood volume and CA125 levels in treatment group were significantly lower than those in control group [ （ 11 ± 3 ）% vs. （45 ± 6）%, （7.01 ±2.97） U/L vs. （38.79 ±31.43） U/L] （P 〈0.05）. The recurrence rate in treatment group was significantly lower than that in control group [ 2.38% （ 1/42 ） vs. 28.57% （ 12/42 ）,P 〈 0.05 ]. Conclusion Endometriosis set levonorgestrel IUD after therapy can relieve postoperative pain and reduce menstiual flow,reduce lesion recurrence rate, its clinical effect is significant.
出处
《中国医师进修杂志》
2013年第36期24-26,共3页
Chinese Journal of Postgraduates of Medicine
