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子宫动脉栓塞术联合甲氨蝶呤治疗剖宫产术后子宫瘢痕妊娠的临床疗效观察 被引量:21

The Observation of the Clinical Effect of Uterine Artery Embolization Combined with Methotrexate in the Treatment of Uterine Scar Pregnancy After Cesarean Section
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摘要 目的:为了进一步研究和探讨子宫动脉栓塞术联合甲氨蝶呤治疗剖宫产术后子宫瘢痕妊娠的临床效果,为相关的临床研究提供借鉴和参考。方法:选取本院2010年12月-2012年12月收治的138例剖宫产术后子宫瘢痕妊娠患者为研究对象,按照随机数字表法将其分为A组和B组各69例,A组给予全身甲氨蝶呤治疗,B组给予子宫动脉栓塞术联合局部注射甲氨蝶呤治疗。观察比较两组患者治疗后子宫内包块消失时间、血清β-hCG恢复正常时间、住院时间以及临床治愈情况。结果:两组患者采用不同临床治疗方法后,B组患者在子宫内包块消失时间、血清β-hCG恢复正常时间和住院时间上均明显优于A组患者,比较差异均有统计学意义(P<0.05)。且B组治愈率明显高于A组,差异有统计学意义(P<0.05)。结论:在临床治疗剖宫产术后子宫瘢痕妊娠的实践过程中,采用子宫动脉栓塞术联合甲氨蝶呤治疗的临床效果显著,是临床治疗剖宫产术后子宫瘢痕妊娠的可靠选择。 Objective:To further study and discuss the clinical therapeutic effect of uterine artery embolization combined with methotrexate in the treatment of uterine scar pregnancy after cesarean section,so as to provide reference for the related clinical research.Method:One hundred and thirty-eight patients with uterine scar pregnancy after cesarean section in our hospital from December 2010 to December 2012 were chosen as the research objects,they were randomly divided into the group A and the group B,69 cases in each group.The group A was given systemic methotrexate treatment, the group B was given uterine artery embolization combined with local injection of methotrexate therapy.Uterine mass disappearing time,serum β-hCG recovery time,hospitalization time and clinical cure the two groups after treatment were observed and compared.Result:After different clinical treatment methods for the two groups,the uterus for mass disappearing time,serumβ-hCG recovery time and hospitalization time in the group B were significantly higher than those in the group A,the differences were statistically significant(P〈0.05).And the cure rate of group B was significantly higher than that of group A,the difference was statistically significant(P〈0.05).Conclusion:In clinical practice for treatment of cesarean scar pregnancy,the clinical treatment effect of uterine artery embolization combined with methotrexate is significant,and it is a reliable choice of uterine scar after cesarean section.
作者 刘冬梅
出处 《中国医学创新》 CAS 2013年第35期43-44,共2页 Medical Innovation of China
关键词 子宫动脉栓塞术 甲氨蝶呤 剖宫产术后子宫瘢痕妊娠 临床疗效 Uterine artery embolization Methotrexate Pregnancy on cesarean section scar Clinical effect
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