摘要
目的探讨白内障手术围术期实施药学干预的临床效果。方法对温州医科大学附属眼视光医院药剂科2011年1～12月实施药学干预的白内障手术围术期患者70例作为研究组,并选取温州医科大学附属眼视光医院药剂科2010年1～12月未实施施药学干预的白内障手术围术期患者70例作为对照组,观察两组患者切口感染情况、抗菌药物使用情况、住院时间、住院费用和抗菌药物治疗费用以及抗菌药物种类等。结果①研究组患者切口感染率[1.4%(1/70)]和抗菌药物使用不合理率[0.0%(0/70)]均明显低于对照组切口感染率和抗菌药物使用不合理率[10.0%(7/70)、7.1%(5/70)],差异均有统计学意义(P<0.05)。②研究组住院时间[(7.8±0.7)d]、住院费用[(0.41±0.02)万元]、抗菌药物治疗费用[(0.10±0.01)万元]以及抗菌药物种类[(1.1±0.2)种]均明显低于对照组患者住院时间[(9.3±1.2)d]、住院费用[(0.62±0.07)万元]、抗菌药物治疗费用[(0.27±0.02)万元]以及抗菌药物种类[(0.27±0.02)种],差异有统计学意义(P<0.05)。③研究组术后5 d体温[(37.03±0.16)℃]明显低于对照组术后5 d体温[(38.33±0.21)℃],差异有统计学意义(P<0.05)。结论临床中对白内障手术患者围术期加强药学干预是可行的,能够有效降低术后切口感染,进一步规范患者临床用药。同时,针对性的药学干预措施能够缩短患者住院时间、降低治疗费用,整个干预措施效果明显,针对性强,值得临床中应用与推广。
Objective To investigate the clinical effect of pharmaceutical intervention on prevention of cataract operation during perioperative period. Methods 70 cases of cataract surgery with perioperative pharmacy interventions in Department of Pharmacy,the Affiliated Eye Hospital of Wenzhou Medical University from January to December in 2011 were selected as research group; 70 cases of cataract surgery without perioperative pharmacy interventions in Department of Pharmacy,the Affiliated Eye Hospital of Wenzhou Medical University from January to December in 2010 were chosen as control group. Incision infection situation,antimicrobial drug usage situation,hospital stays,hospitalization expenses,antimicrobial drug expenses,antibacterial drug kinds between the two groups were observed. Results ①The wound infection rate and irrational use rate of antibiotics in research group [1.4%（1/70）,0.0%（0/70）] were lower than those in control group [10.0%（7/70）,7.1%（5/70）],the differences were statistically significant（P 〈0.05）. ②Hospital stays,hospitalization expenses,antimicrobial drug expenses,antibacterial drug kinds in research group [（7.8±0.7） d,（0.41±0.02） million yuan,（0.10±0.01） million yuan,（1.1±0.2） kinds] were all lower than those in control group [（9.3±1.2） d,（0.62±0.07） million yuan,（0.27±0.02） million yuan,（0.27±0.02） kinds],the differences were statistically significant（P 〈0.05）. ③The body temperature 5 days after the operation in research group [（37.03±0.16）℃] was lower than that in control group [（38.33±0.21）℃],the difference was statistically significant（P 〈0.05）. Conclusion It is feasible to take the pharmaceutical intervention on cataract operation during perioperative period in clinical practice. It can effectively reduce postoperative wound infection,standardize clinical drug use. Meanwhile,the implementation of targeted pharmaceutical interventions can shorten the patients＇ length of stay and cost of treatment,the who
出处
《中国医药导报》
CAS
2013年第36期166-168,共3页
China Medical Herald
基金
教育部高等学校博士学科点专项科研基金项目(编号20080 3350064)
关键词
白内障手术
围术期
药学干预
用药影响
Cataract surgery
Perioperative
Pharmaceutical intervention
Drug effects
