摘要
目的:明胶空心胶囊检测环氧乙烷在FID检测器中响应值低,对结果的干扰较大,容易出现假阳性的情况。现对实验中遇到的假阳性情况提出讨论,对出现环氧乙烷超标的情况给予警醒。方法:采用气相色谱法分别用两种不同极性的DB-WAX色谱柱和HP-5色谱柱测定同一样品中的环氧乙烷。结果:使用DB-WAX色谱柱测定样品环氧乙烷残留量超出标准规定;使用HP-5色谱柱测定样品中未检出环氧乙烷。结论:由于环氧乙烷峰面积小,出峰时间快,样品杂质峰多,容易被杂质干扰,建议出现残留量不合格时用不同极性色谱柱复试。
Objective：The gelatin hollow capsule detection of epoxy ethane in the FID response value is low, the result of the disturbance is larger, prone to false positives. Of false positives is also discussed in the experiment, the epoxy ethane exceeds the condition to give alert. Methods ： Using gas chromatography, respectively in two different polarity of DPrWAX and HP-5 chromatographic column for determination of epoxy ethane in the same sample. Results： To use the DB-WAX for chromatographic column sample epoxy ethane residues beyond the prescribed standards; Use HP-5 chromatographic column did not check out the epoxy ethane in the samples. Conclusion：Because of epoxy ethane peak area is small, the peak time is fast, impurity peaks of samples, the results are easy to be interference of impurities, suggest resi- due apoear unqualified when use different polarity column second-round exam.
出处
《亚太传统医药》
2013年第12期53-54,共2页
Asia-Pacific Traditional Medicine
