摘要
目的 :比较曲马多、吗啡用于术后病人自控硬膜外镇痛 (PCEA)的临床效应 ;方法 :选择 12 0例ASAⅠ～Ⅱ级下腹部手术病人 ,随机分成二组 ,分别为T组 (n =60 ) :10 0ml药液含曲马多 50 0mg、2 %利多卡因 2 0 0～ 30 0mg ,氟哌利多 5mg ;M组 (n =60 ) :10 0ml药液含吗啡 6mg、2 %利多卡因 2 0 0～30 0mg、氟哌利多 5mg。镇痛泵采用Baxter一次性微量连续泵 ,自控速率 2ml/h ,镇痛时间为 50h ;结果 :①镇痛效果 :两组疼痛的视觉模拟评分 (VAS)优良率无明显差别。②两组首 2 4h用药量均相对较多。③镇痛期间Bp、HR、无异常波动 ,未出现呼吸抑制 ,恶心呕吐 ,T组 2例 ,M组 3例 ,瘙痒 ,T组无 ,M组 1例 ;结论 :等效剂量曲马多和吗啡镇痛效果比较发现 ,二组镇痛VAS优良率无明显区别。但曲马多并发症少于吗啡 ,尤其复合低浓度局麻药及少量镇静药使用时 ,是一种完全、有效的PCEA用药。
OBJECTIVE:To compare the clinical effects of postoperative patient controlled epidural analgesia (PCEA)with Tramadol or Morphine. METHOD:120 cases of low-abdomen surgical patients were randomly divided into 2 groups:Tramadol (group T)mixture of tramaldol 500mg,2%Lidocaine 200～300 mg and Droperidol 5mg,Morphne (group M),mixture of Morphine 6mg,2% Lidocaine 200～300 mg and Droperidol 5 mg,with a Baxter PCA pump,the injection rate is 2 m/h. RESULT:①in the two groups,the visual analog scale scores is similar.②in the first postoperative 24 hours,the amount of drugs used in each group was similar.③The incidence of nausea and vomitting ,group M was a little higher than group T.Group M had pruritus. CONDLUSION:The effects of postoperative patient controlled epidural with Tramadol or Morphine is similar.But the incidence of group Tramadol is lower than group Morhpine,especially combination of analgesic and sedative.
出处
《航空航天医药》
2000年第4期209-210,共2页
Aerospace Medicine
关键词
曲马多
吗啡
手术后
自控硬膜外镇痛
Tramadol Morphine postoperative patient controlled epidural analgesia
