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实行心肌超声造影评价经皮冠状动脉介入治疗的临床疗效 被引量:4

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摘要 目的应用实时心肌超声造影(RTMCE)检测急性心肌梗死(AMI)后梗死区域心肌微循环灌注,比较药物治疗和经皮冠状动脉支架介入(PCI)疗效。方法 AMI后3~28 d的患者10例为药物治疗组,20例为PCI组,分别于治疗前后1个月行实时心肌超声造影,观察治疗前后各指标的比值即心肌血流量储备值的变化,并观察治疗1个月后主要不良心脏事件。结果药物治疗组治疗前后心肌灌注显像时间无差异(P>0.05),造影计分指数CSI为〔(1.63±0.25)vs(1.58±0.17),P>0.05〕;心肌血流量(A、β)分别为〔(1.01±0.27)、(1.39±0.15)vs(1.07±0.15)、(1.44±0.28),P>0.05〕,但A·β治疗前后〔(1.45±0.54)vs(1.56±0.52),P<0.05〕。PCI组术后心肌灌注时间缩(P<0.01),CSI为〔(1.50±0.39)vs(1.72±0.17),P<0.01〕;A、β分别为〔(1.09±0.25)、(1.38±0.27)vs(1.51±0.33)、(1.66±0.23),P<0.01〕,A·β分别为〔(2.88±0.9)vs(1.56±0.63),P<0.01〕。两组治疗1个月后主要不良心脏事件无明显统计学意义(P>0.05)。结论 RTMCE可定性、定量评价心肌微循环灌注,PCI可有效改善AMI后3~28 d患者心肌微循环灌注,但小样本短期观察对比药物治疗PCI无明显临床获益。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2013年第24期6080-6081,共2页 Chinese Journal of Gerontology
基金 福建省南平市科技局基金(No.N2009Z32-2)
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