摘要
为探讨儿童白血病和恶性淋巴瘤血小板显著减少期输注单采血小板的疗效，对１００例急性白血病和非霍奇金氏淋巴瘤患儿输注单采血小板１单位后１８ｈ～２４ｈ测定外周血血小板计数，计算纠正计数指数（ＣＣＩ）和回升率及观察临床疗效。结果：９９例临床出血症状改善，１例因白血病复发全身衰竭、出血死亡，输注后血小板平均升高５３．４１×１０＾９／Ｌ。（Ｐ〈０．０１）；平均回升率３４．９％。血小板输注无效３０例（３０．０％）。结果表明，儿童白血病和恶性肿瘤血小板减少期输注单采血小板后临床止血效果好，副反应小。
To explore the effect of single-donor platelet transfusion for the supportive therapy of childhood leukemia and malignant lymphoma, the single-donor platelet was infused in 100 cases with either acute leukemia or non-Hodgkin lymphoma. The platelet count was measured during 18-24 hours after platelet transfusion. The corrected count index (CCI) and the recovery rate were also calculated. The results showed that the clinical symptom of bleeding improved in 99 cases except for one case who was died from a system failure and bleeding owing to recurrent leukemia. An average of increased platelet was 53. 41 × 109/L and the recovery rate was 34.9% after platelet transfusion. It is concluded that single-donor platelet transfusion is valuable for the arrest of bleeding in childhood leukemia and malignant lymphoma with minor side reaction clinically.
出处
《临床儿科杂志》
CAS
CSCD
北大核心
2000年第6期325-326,共2页
Journal of Clinical Pediatrics
关键词
单采血小板输注
白血病
恶性淋巴瘤
儿童
single donor platelet transfusion platelet counts leukemia lymphoma
