摘要
目的探讨右美托咪定预防静吸全麻下宫颈癌根治手术后苏醒期中的寒战效果。方法选取2010年10月~2012年5月本院收治的选择宫颈癌根治术患者共60例,随机分为治疗组和对照组,其中治疗组于气管插管后静脉输注右美托咪定,而对照组在相同时段内静脉输注等容量的生理盐水。结果治疗组患者的手术时间、麻醉时间、拔管时间均略少于对照组患者,但差异不存在统计学意义（P〉0.05）;治疗组苏醒期的寒战发生率与寒战发生程度均显著低于对照组（P〈0.05）;治疗组入恢复室时及入恢复室后0.5 h、1 h的Ramsay镇静评分均明显高于对照组（P〈0.05）,而入恢复室时、0.5 h的视觉模拟评分均明显低于对照组（P〈0.05）。结论宫颈癌静吸全麻维持期静脉输注右美托咪定,可以有效地预防术后寒战的发生,且不影响苏醒时间。
Objective To determine the effect of dexmedetomidine on preventing shiver with general anesthesia after radical removal of cervical carcinoma in the up period. Methods A total of 60 patients with radical removal of cervical carcinoma from October 2010 to May 2012 were divided into 2 groups. The treatment group used dexmedetomidine with venoclysis after trachea cannula while the control group used normal saline with same capacity at the same time. Results The time of operation, anesthesia and tube drawing of the treatment group was shorter than those of the control group, with no significant difference（P 0.05）. The incidence and degree of shiver in the treatment group were obviously lower than those in the control group（P 0.05）. After entering recovery room, the Ramsay sedation score in the treatment group was higher than that in the control group（P 0.05） while the VAS score was lower than that in the control group（P 0.05）. Conclusion Dexmedetomidine in the maintenance period of general anesthesia for cervical carcinoma can effectively prevent shiver without affecting the recovery time.
出处
《中南药学》
CAS
2013年第11期871-873,共3页
Central South Pharmacy
关键词
右美托咪定
预防
全身麻醉
宫颈癌根治手术
寒战
dexmedetomidine
prevention
general anesthesia
radical operation of cervical carcinoma
shiver
