摘要
目的 探讨醋酸甲羟孕酮治疗子宫内膜不典型增生的效果.方法 选择本院2012年5月～2013年8月收治的子宫内膜不典型增生患者56例,随机分为研究组和对照组,每组各28例,研究组患者给予醋酸甲羟孕酮治疗,2 mg/d,2次/d;对照组患者口服戊酸雌二醇片,1 mg/d;两组患者均治疗3个月,观察两组患者的治疗效果,采用PBAC评分观察治疗前后月经或阴道出血情况.结果 治疗后研究组总有效率明显低于对照组,两组差异有统计学意义.治疗后研究组阴道出血情况明显改善,PBAC评分明显高于对照组,两组差异有统计学意义.结论 醋酸甲羟孕酮治疗子宫内膜不典型增生疗效显著,可有效改善患者的出血症状,费用较低,适合患者长期治疗.
Objective To investigate the clinical effect of medroxyprogesterone acetate（DMPA） in treatment of atypical endometrial hyperplasia. Methods 56 patients with atypical endometrial hyperplasia in our hospital from May 2012 to August 2013 were randomly divided into study group and the control group,28 cases in each group,the study group was given medroxyprogesterone acetate treatment,2 mg/d,2 times/d;The control group was treated with estradiol valerate tablets,1 mg/d,two groups of patients were treated for 3 months,treatment effects were observed,PBAC score before and after treatment was used to observe menstrual or vaginal bleeding. Results After treatment total effect rate of study group was significantly higher,the difference was statistically significant.Vaginal bleeding of the study group improved significantly after treatment,PBAC score was significantly lower,the difference was statistically significant. Conclusion The effect of medroxyprogesterone acetate treatment of endometrial atypical hyperplasia is significant,it can efffectively improve the bleeding symptoms,and cost is lower, it is suitable for long-term treatment of patients.
出处
《中国当代医药》
2013年第35期84-84,86,共2页
China Modern Medicine
关键词
醋酸甲羟孕酮
子宫内膜不典型增生
药物治疗
Medroxyprogesterone acetate
Atypical endometrial hyperplasia
Drug treatment
