摘要
目的：探讨纳洛酮治疗脑血栓的临床应用和疗效。方法：选取我院在2010年～2012年收治的脑血栓患者80例，将所有患者随机分为观察组和对照组，对照组给予常规治疗，观察组在常规治疗的基础上加用盐酸纳洛酮治疗，对2组的治疗效果进行比较。结果：（1）2组疗效的比较，观察组总有效率（92．5％）明显大于对照组（77．5％），且P〈0．05；（2）对2组患者神经功能缺损情况的比较，治疗前2组无明显差异P〉0．05，治疗后，观察组神经功能缺损改善情况明显优于对照组，且P〈0．05。结论：在常规治疗的基础上，加用纳洛酮治疗脑血栓患者疗效确切，可明显改善患者的临床症状，值得推广。
Objective：To investigate the clinical application and effect of naloxone for treatment of cerebral thrombosis. Methods：We selected 80 patients with cerebral thrombosis treated in our hospital irom 2010 to 2012. All patients were randomly divided into observation group and control group. The control group was given conventional treatment, while the observation group was added naloxone hydrochlo- ride to conventional treatment. The effect of＇ treatment in the two groups was compared. Results： Firstly, the clinical effect of the two groups was compared. The total effective rate of observation group（92.5% ）was obviously higher than control group（77.5% ）, and there was an significant difference between the two groups （ P 〈 O. 05 ） ; Secondly, neurologic deficits of patients in the two groups were com- pared. There was no difference between the two groups before treatment （ P 〉 0.05 ）. But after treatment, the improvement of neurologic deficits of the observation group was obviously better than control group （ P 〈 0.05 ）. Conclusion ： The use of naloxone on the base of con- ventional therapy in the treatment of cerebral thrombosis had an accurate efficacy, and it significantly improves the patients＇ clinical symp- toms. It should be worthy of promotion.
出处
《中国伤残医学》
2013年第12期28-29,共2页
Chinese Journal of Trauma and Disability Medicine
关键词
纳洛酮
脑血栓
应用
疗效观察
Naloxone
Cerebral thrombosis.
Application
Clinical observation
