摘要
目的 :初步探讨食管癌患者外周血白细胞介素 - 8(以下简称 IL - 8)含量变化的临床价值。方法 :应用酶联免疫吸附 (EL ISA)法对 34例食管癌患者外周血 IL- 8含量进行检测 ,并与正常人进行比较分析。结果 :肿瘤患者外周血 IL- 8含量显著高于正常人对照组 ,且与临床分期有关。 IL- 8含量升高与组织类型、分化程度、年龄、性别未显示统计学差异。结论 :内源性 IL - 8水平升高是机体抗肿瘤免疫反应之一。 IL - 8检测可作为食管癌辅助诊断和病情监测的参考指标。
Objective:To study the activity and clinical significance of IL-8 in patients with esophageal carcinoma.Method:The peripheral blood IL-8 level of 34 patients with esophageal carcinoma were measured by Enzyme Linked Inuno Sorbenot Assay(ELISA).Result:The level of IL-8 in the peripheral blood was significantly higher than the normal control group ( P <0.01),and was relative to the clinical staging.Conclusion:IL-8 may not only reflect the immune state of the malignant tumors,but also serve as a indicator in the supplementary diagnosis and monitoring the condition of the malignant tumors.
出处
《山西临床医药》
2000年第11期813-814,共2页
Shanxi Clinical Medicine
