摘要
目的了解诺如病毒(NOV)聚集性胃肠炎疫情密切接触者病毒感染及环境污染情况。方法选取3起养老机构NoV聚集性胃肠炎疫情,采集患者、无症状密切接触者的粪便或肛拭子,院内环境表面涂抹样本,采用实时荧光RTPCR进行NoV核酸检测。结果 3起疫情报告病例59例,涉及老年病例56例,护工3例,罹患率在15.71%～37.67%,平均罹患率为25.00%;无症状密切接触者41人,NoV阳性者15人,感染率为36.59%,其中护工11人,感染率为32.35(11/34),保洁、保健医生各2人;环境样本27份,污染率为37.04%(10/27),其中马桶表面污染4份、床单元3份、扶梯2份、门把手1份。结论诺如病毒胃肠炎疫情中密切接触者病毒隐性感染较多,院内环境存在病毒污染,应加强患者密切接触者的管理和院内环境的消毒,防止疫情扩散。
Objective To understand the norovirus infection status of close contacts of norovirus gastroenteritis and the environ- ment contamination in three nursing homes. Methods Feces and anal swabs from patients and asymptomatic close contacts and environmental samples were collected to detect NoV nucleic acid by real - time RT - PCR. Results In 3 nursing homes, 59 norovirus gastroenteritis cases were reported, including 56 elders and 3 nursing workers, the attack rate was between 15.71% and 37.67%, the average attack rate was 25.00% ; Forty - one asymptomatic close contacts of patients were included in this survey, the infection rate of norovirus was 36.59% （15/41）, including 11 nursing workers, 2 cleaners and 2 health care physi- cians ; Among 27 environment samples, the positive rate of norovirus was 37.04% （10/27）. Conclusion The infection rate of norovirus in close contacts of patients is high and the norovirus contamination exists in environment of three nursing homes. Man- agement of close contacts and disinfection of the environment are important for control of norovirus gastroenteritis.
出处
《中国卫生检验杂志》
北大核心
2013年第16期3290-3292,共3页
Chinese Journal of Health Laboratory Technology
基金
上海市卫生局青年科研项目(20114y026)
金山区科委创新基金项目(2011-3-09)
关键词
诺如病毒
急性胃肠炎
密切接触者
环境
Norovirus
Acute gastroenteritis
Close contacts
Environment
