摘要
目的:探讨儿童肺炎支原体肺炎(MMP)临床表现和发病机制。方法:从2011年6月～2012年6月间该院收治的确诊为肺炎患儿中筛选得到310例,依据临床表现、实验室检查及影像学表现,分为MMP组(145例)和非MMP组(165例),对比分析两组患儿的各项临床资料。结果:MMP组患儿发热、咳嗽、喘息的天数均高于非MMP组患儿,差异有统计学意义(P<0.05),MMP组肺部湿啰音患儿数小于非MMP组,差异有统计学意义(P<0.01);MMP组患儿红细胞和血小板计数低于非MMP组患儿,差异有统计学意义(P<0.05);MMP组患儿各项病原检查项目阳性率均高于非MMP组,差异有统计学意义(P<0.05);两组患儿IgA、IgM、IgG、C3、C4水平差异有统计学意义(P<0.05)。结论:MMP患儿发热、咳嗽、喘息的时间较长,容易出现混合病原体感染,在临床工作中要格外注意;MMP发病机制可能与体液免疫有关。
Objective： To explore the clinical manifestations and pathogenesis of Mycoplasma pneumoniae pneumonia （MMP） in children. Methods： A total of 310 MMP children diagnosed definitely in the hospital from June 2011 to June 2012 were selected and divided into MMP group （ 145 children） and non - MMP group （ 165 children） according to clinical manifestations, laboratory examination, and ima- ging manifestations; the clinical data of children in the two groups were compared and analyzed. Results： The duration days of fever, cough, and wheezing in MMP group were statistically significantly higher than those in non - MMP group （P 〈 0. 05 ）, the number of chil- dren with lung wet rales in MMP group was statistically significantly lower than that in non - MMP group （P 〈 0. 01 ） ; the counts of red blood cells and platelets in MMP group were statistically significantly lower than those in non - MMP group （ P 〈 0. 05 ） ; the positive rates of patho- genic examination items in MMP group were statistically significantly higher than those in non - MMP group （P 〈 0. 05） ; there were statisti- cally significant differences in the levels of IgA, IgM, IgG, C3 and C4 between the two groups （P 〈 0. 05 ） . Conclusion ： The duration times of fever, cough, and wheezing in MMP children are long, mixed pathogen infection is easily to occur, which should be paid more atten- tion to in clinical work; the pathogenesis of MMP is related to humoral immunity.
出处
《中国妇幼保健》
CAS
北大核心
2013年第34期5647-5649,共3页
Maternal and Child Health Care of China
关键词
儿童
肺炎支原体肺炎
临床表现
发病机制
Child
Mycoplasmapneumoniae pneumonia
Clinical manifestation
Pathogenesis
