期刊文献+

松弛素与早产胎膜早破的相关性临床研究 被引量:1

下载PDF
导出
摘要 目的:观察松弛素(RLN)与早产胎膜早破的相关性。方法:选择2011年1月~2012年12月在我院住院的胎膜早破患者110例,分为观察组(早产胎膜早破组)56例、对照组(足月胎膜早破组)54例。以ELISA法检测血清RLN2水平,冉以免疫组化法测定胎膜和胎盘组织中的松弛素受体蛋白LCR7的表达,进行综合分析。结果:观察组血清RLN2水平(373.87±142.12)pg/ml,对照组血清RLN2水平(282.74±96.14)pg/m1,两组相比差异有统计学意义(P〈0.05)。观察组松弛素受体蛋白LGR7强阳性表达率为96.4%(54/56),对照组松弛素受体蛋白LGR7强阳性表达率为77.8%(42/54),两组相比差异有统计学意义(P〈0.05)。胎膜和胎盘组织中的松弛素受体蛋白LGR7表达水平与血清RLN2水平呈正相关关系,Peasrong相关系数为0.713(P〈0.05),具有统计学意义。结论:血清RLN2水平及胎膜和胎盘组织中的松弛素受体蛋白表达的增高可能与早产胎膜早破的发生有关。
作者 刘园园
出处 《中国民康医学》 2013年第22期60-60,共1页 Medical Journal of Chinese People’s Health
  • 相关文献

参考文献3

二级参考文献30

  • 1Bryant - Greenwood GD, Schwabe C. Human relaxins : chemistry and biology [ J ]. Endocr Rev, 1994,15:5 - 26. 被引量:1
  • 2Hsu SY, Kudo M, Chen T, et al. The lhree subfamilies of leucine -rich repeat - containing G protein - coupled receptors ( LGR7 ) : identification of LGR6 and LGR7 and the signaling mechanism for LGR7 [ J ]. Mol Endocrinol, 2000,14 : 1257- 71. 被引量:1
  • 3Hsu SY, Nakabayashi K, Nishi S, et al. Activation of orphan receptors by the hormone relaxin[ J]. Science,2002,295:671 -4. 被引量:1
  • 4Ivell R, Balvers M, Pohnke Y, et al. Immunoexpression of the relaxin receptor LGR7 in breast and uterine 1issues of humans and primates [ J]. Reprod Biol Endocrinol,2003,1 : 114. 被引量:1
  • 5Luna JJ, et al. Gene expression pattern and immunoreaetive protein localization of LGR7 receptor in human endometrium throughout the menstrual cyele[JJ. Mol Hum Reprod, 2004,10:85 -90. 被引量:1
  • 6Bond CP, et al. Increased expression of the relaxin receptor ( LGR7 ) in human endometrium during the secretory phase of the menstrual cycle[J]. Clin Endocrinol Metab,2004,89:3477 85. 被引量:1
  • 7Shirota K, Tateishi K, Koji T, et al. Early human preantral follicles have relaxin and relaxin receptor ( LGR7 ), and relaxin promotes their development[JJ. Clin Endocrinol,2005 ,90 :516 21. 被引量:1
  • 8Liu J, Feng ZC, Wu J. The incidence rate of premature rup- ture of membranes and its influence on fetal - neonatal health., a report from China's Mainland. Journal of tropical pediatrics, 2010, 56.. 36-42. 被引量:1
  • 9Getahun D, Ananth CV, Oyelese Y, et al. Acute and chronic respiratory diseases in pregnancy: associations with spontane- ous premature rupture of membranes. J Matern Fetal Neo- natal Med, 2007, 20: 669-675. 被引量:1
  • 10Vogel I, Salvig JD, Seeher NJ, et al. Association between raised S- relaxin during the eighteen gestation week and very preterm delivery. Am J Obstet Gynecol, 2001, 184 390 - 393. 被引量:1

共引文献224

同被引文献4

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部