摘要
石墨烯衍生物是利用氧化石墨烯表面的含氧官能团进行化学修饰而形成的复合炭材料。在兼备石墨烯非凡的物理及化学性质基础上,石墨烯衍生物还具有优良的水溶性和生物相容性,从而拓展了石墨烯的应用领域。综述石墨烯衍生物在肿瘤治疗方面的研究进展,主要包括生物成像、纳米载药及光动力疗法,为其在生物医药领域的进一步应用提供了新方法和新思路。
Graphene derivatives generated by modifying the surface oxygen functional groups of graphene oxide have been widely investigated in recent years.Graphene derivatives possess excellent aqueous solubility and biocompatibility similar to graphene oxide,which are important in their biomedical application.Research progress on the use of graphene derivatives in biological imaging,drug carriers and photodynamic therapy of cancer is presented.Future efforts to improve their performance in cancer therapy are also proposed,such as lowering the toxic effects introduced by chemicals used in the preparation of the graphene derivatives,expanding the drug to include genes and proteins,and coupling photodynamic therapy with imaging.
出处
《新型炭材料》
SCIE
EI
CAS
CSCD
北大核心
2013年第5期321-326,共6页
New Carbon Materials
基金
国家自然科学基金(51172152
51242007)
山西省自然科学基金(20100011033-2)~~
关键词
石墨烯衍生物
肿瘤治疗
光动力
药物载体
Graphene derivatives
Cancer therapy
Photodynamic
Drug carriers
