摘要
目的探讨阿奇霉素联合痰热清治疗小儿肺炎支原体肺炎的临床疗效。方法将2010年1月至2011年12月入住余杭区第一人民医院儿科确诊肺炎支原体肺炎的患儿98例按就诊顺序分为两组,对照组选用阿奇霉素序贯疗法,观察组采用阿奇霉素和痰热清联合治疗,两组各治疗1个疗程后观察患儿临床疗效。结果观察组总有效率为98.0%;对照组总有效率为83.7%,两组总有效率比较差异有统计学意义(x^2=7.85,P<0.05)。观察组咳嗽消失时间、体温恢复正常时间、干湿罗音消失时间均低于对照组,两组比较差异均有统计学意义(t值分别为10.85、12.92、9.88,均P<0.01)。观察组不良反应1例,占2.0%,对照组不良反应6例,占12.2%,两组不良反应发生率比较差异有统计学意义(x^2=2.84,P<0.05)。结论阿奇霉素与痰热清联合应用治疗小儿肺炎支原体肺炎,临床效果显著,可有效改善患者各方面临床症状和体征,毒副作用小,并可大大缩短病程,避免并发症的发生,具有积极的临床意义。
Objective To explore the clinical efficacy of azithromycin combined with Tanreqing in the treatment of mycoplasma pneumoniae pneumonia .Methods Totally 98 cases were diagnosed with mycoplasma pneumonia in the First People ＇ s Hospital of Yuhang District in the period of January 2010 to December 2011.They were divided into two groups according to diagnosis order .The control group was treated with azithromycin sequential therapy , while the observation group accepted azithromycin combined with Tanreqing .After one course of treatment clinical efficacy of two groups was observed .Results The total effective rate was 98.0%in the observation group and 83.7%in the control group.The total effective rate was significantly different （χ^2 =7.85, P〈0.05）.Disappearance of cough, body temperature returning to normal , wet and dry rales disappearance were earlier in the observation group than the control group , and the differences were statistically significant （t value was 10.85, 12.92 and 9.88, respectively, all P〈0.01）.Adverse reactions occurred in 1 case （2.0%） in the observation group and in 6 cases （12.2%） in the control group .The difference in the incidence of adverse reactions was statistically different （χ^2 =2.84,P〈0.05）.Conclusion Azithromycin combined with Tanreqing is effective in treatment of mycoplasma pneumoniae pneumonia , and can effectively improve all aspects of patient clinical signs and symptoms .The side effects are mild .It can greatly shorten course of disease and avoid complications with positive clinical significance .
出处
《中国妇幼健康研究》
2013年第5期687-689,共3页
Chinese Journal of Woman and Child Health Research
