摘要
老龄化虽然带来不可避免的免疫能力下降,但机体在受到创伤之后仍会引起自然免疫和获得性免疫两种免疫反应。这两种免疫反应可导致严重的并发症(如全身炎性反应综合征,多器官功能衰竭等),甚至死亡,所以对严重创伤后免疫功能紊乱的治疗及试验研究是很重要的,尤其是对老年患者。目前针对老年人创伤后高病死率这一问题的研究涉及很多方面,但由于创伤机制复杂,许多难题仍然有待解决。
Though aging does lead to an unavoidable decline in immune functions, natural inmmnity and acquired immunity can still be induced after trauma, which can result in serious complications（ for example systemic inflammatory response syndrome, muhiorgan dysfunction syndrome） , or even death. Therefore the studies on the treatment and trial of disordered immune function after severe trauma is very important, espe- cially in the elderly. Until now, there are many researches on the high mortality after trauma in the elderlyfrom different aspects or different methods, still a lot of problems are to be solved due to the complicated mecha- nisms of trauma.
出处
《医学综述》
2013年第19期3500-3503,共4页
Medical Recapitulate
关键词
创伤
性别
输血
手术
免疫
Trauma
Gender
Blood transfusion
Operation
hnmune
