摘要
目的:考察超滤技术对清喉颗粒的除杂效果。方法:以绿原酸、总黄酮、牛蒡子苷保留率及固形物减少率为指标,对膜分子量、药液比、温度、加水量等4因素进行考察。结论:确定超滤工艺为:药液比为1∶16(g/ml)的药液,在40℃条件下进行超滤(超滤膜的截留分子量为20万),在超滤过程中补加5倍量水。采用超滤技术对药液进行除杂,能够有效去除药液中的热原,提高药液澄明度,较大程度保留有效成分。
Objective：To study the impurity-removing effect of the ultrafiltration technique on throat-cleansing powder.Method：With the retention rate of chlorogenic acid,total flavonoids,and arctiin,and solids reduction rate set as indices,membrane molecular weight,solute-to-solvent ratio,temperature and the amount of water added are examined.Conclusion：The optimal ultrafiltration technique is determined to be：solute-to-solvent ratio at 1：16（g/ml）;ultrafiltration conducted at 40°C（molecular weight cut-off at 2×105）;5times as much as the original amount of water added in.The ultrafiltration method proves effective in removing the pyrogens in the solution,improving its transparency,and retaining the effective ingredients.
出处
《内蒙古石油化工》
CAS
2013年第15期4-6,共3页
Inner Mongolia Petrochemical Industry
关键词
超滤
绿原酸
总黄酮
牛蒡子苷
Ultrafiltration
Chlorogenic acid
Total flavonoids
Arctiin
