摘要
目的:制定独一味环烯醚萜苷胶囊的质量标准。方法:以薄层色谱法对本品主成分进行定性鉴别,采用一阶导数法测定总环烯醚萜苷含量,高效液相色谱法测定山栀苷甲酯、8-O-乙酰山栀苷甲酯的含量。结果:薄层色谱法样品与对照品在相同位置斑点清晰;一阶导数分光光度法测得3批总环烯醚萜苷含量均>50%;山栀苷甲酯、8-O-乙酰山栀苷甲酯与其他组分基线分离且峰形较好,测得3批样品平均含量为73.96,72.43 mg·g-1。结论:该方法可以用于独一味环烯醚萜苷胶囊的质量控制。
Objective：To establish the quality standard of iridoid glycosides capsule of Lamiophlomis rotata （IGC）.Method：The iridoid glycosides capsule of L.rotata was identified by TLC.The contents of total iridoid glycosides,shanzhiside methyl ester and 8-O-acetylshanzhiside methyl ester in the capsule were determined by the first derivating UV-spectra and HPLC.Result：The identify spots were clear in TLC,and the constituents were well separated under the chromatographic condition.The contents of total iridoid glycosides of three batch capsule were more than 50%,the shanzhiside methyl ester and 8-O-acetylshanzhiside methyl ester were separated with other composition and the content were 73.96,72.43 mg ·g-1 respectively.Conclusion：The method can be used to control the quality of IGC.
出处
《中国实验方剂学杂志》
CAS
北大核心
2013年第22期137-140,共4页
Chinese Journal of Experimental Traditional Medical Formulae
基金
甘肃省科技重大专项(1102FKDA012)
关键词
独一味
环烯醚萜苷胶囊
质量标准
Lamiophlomis rotata
iridoid glycosides capsule
quality standard
