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肺炎支原体感染与川崎病患儿预后的关系 被引量:9

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摘要 目的探讨肺炎支原体(MP)感染与川崎病(KD)预后的关系。方法选择KD患儿34例,采用被动凝集法检测MP-IgM抗体,根据其结果将KD患儿分为无MP感染组(n=18)和MP感染组(n=16)。初诊时对两组患儿进行心脏彩超检查,记录两组冠状动脉扩张情况。检测初诊时、治疗2周时常规的实验室指标(WBC、PLT、CRP、IgE及ESR等)和疾病相关的系统症状评分以及初诊时、出院1个月、出院3个月时的心脏彩超变化情况。结果无MP感染组合并冠状动脉扩张阳性率38.9%,MP感染组合并冠状动脉扩张阳性率75%,MP感染组冠状动脉损伤阳性率高于无MP干扰组(P<0.05)。确诊2周时MP感染组PLT、ESR及疾病相关系统症状评分高于无MP感染组(P<0.05)。出院1个月、3个月时MP感染组合并冠状动脉扩张的患儿冠状动脉变化程度高于无MP感染患儿(P<0.05)。结论 MP感染有可能延长KD患儿的病程,增加冠状动脉扩张的几率,从而影响其预后。
出处 《山东医药》 CAS 2013年第38期36-38,共3页 Shandong Medical Journal
基金 山东省卫生科技项目(2009HZ041)
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