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人附睾蛋白4在子宫内膜癌诊断中的应用 被引量：3

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摘要 子宫内膜癌是女性生殖器官最常见的恶性肿瘤之一,占女性生殖道肿瘤的20%～30%.近年来国内发病率上升,且趋于年轻化,有些地方已跃居妇科生殖道肿瘤首位.子宫内膜癌一直缺乏敏感、特异的肿瘤标记物.CA125是目前子宫内膜癌常用的肿瘤标志物,但仅有11%～33%的子宫内膜癌患者升高,并且在其他妇科良性疾病中也有升高,缺乏很好的可信度.人附睾蛋白4（HE4）是一种新型的肿瘤标记物,在国外已广泛应用于卵巢癌的临床诊断.关于HE4用于子宫内膜癌的早期诊断、病情监测及预后,近来国内外也相继有研究报道.现就HE4结构、组织表达、影响因素及在子宫内膜癌中的应用做一综述.
作者 杨淑丽 苗劲蔚
机构地区 首都医科大学附属北京妇产医院妇瘤科
出处 《中国医刊》 CAS 2013年第11期25-27,共3页 Chinese Journal of Medicine
基金 北京市自然科学基金资助项目(2010)7102056
关键词 子宫内膜癌 附睾蛋白 早期诊断 妇科良性疾病 肿瘤标记物 女性生殖器官 女性生殖道 生殖道肿瘤
分类号 R737.3 [医药卫生—肿瘤]
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参考文献19

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二级参考文献22

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共引文献93

同被引文献34

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引证文献3

二级引证文献35

中国医刊
2013年 第11期

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