摘要
本文着重介绍群体药代动力学的研究设计及其数据库建立,使读者明确群体药代动力学研究设计的关注点以及非线性混合效应模型方法中数据库建立的详细过程和关键点。
The designing population pharmacokinetic studies and building database for model development were introduced in this paper, which was helpful for readers to understand the key points of study design and the detail process of database creation for nonlinear mixed effect modeling approach.
出处
《中国临床药理学杂志》
CAS
CSCD
北大核心
2013年第10期723-727,共5页
The Chinese Journal of Clinical Pharmacology
关键词
群体药代动力学
研究设计
非线性混合效应模型法
数据库
population pharmacokinetic
study design
nonlinear mixed effect modeling approach
database