摘要
目的分析甲状腺癌病例的临床及病理特点，为下一步研究碘营养与甲状腺结节性疾病的关系提供参考。方法收集分析宁波市北仑区人民医院（以下简称“我院”）2006年1月-2012年12月收治144例甲状腺癌患者临床病理资料，记录甲状腺癌年发病例数、年龄、性别、户籍、术前彩超结果、发病部位、病理类型、是否合并其他良性疾病及淋巴转移情况等方面内容。结果2006年一2012年甲状腺癌病例依次为8、10、10、13、23、32、48例，其中男32例，女112例。男性平均发病年龄（37．1±8．2）岁，发病高峰（30～50）岁，女性平均发病年龄（47．0±12．3）岁，发病高峰（25～55）岁。北仑籍120例（83．3％），外省籍24例（16．7％），发病率比较差异有统计学意义（P=0．02）。术前彩超提示甲状腺癌钙化120例（83．3％），其中微小沙粒钙化76例（52．8％）。乳头状癌134例（93．1％），滤泡状癌15例（10．4％），髓样癌1例（0．7％），其中乳头状癌和滤泡状癌共存6例。右叶单发80例（55．6％），左叶单发36例（25．0％），双侧28例（19．4％）。淋巴转移72例，其中男20例（62．5％），女52例（46．4％），差异无统计学意义（P=0．11）。〈45岁淋巴转移46例（59．0％），≥45岁淋巴转移26例（39．4％），差异有统计学意义（P=0．02）；合并其他良性疾病70例，分别为结节性甲状腺肿50例，慢性淋巴细胞性甲状腺炎10例，腺瘤6例，亚急性肉芽肿性甲状腺炎3例，非特异性甲状腺炎1例。结论近7年我院收治的甲状腺癌患者逐年增多，防治过程中要根据发病特点制订相关策略。
Objective To analyze the clinical and pathological features of 144 cases of thyroid carcinoma and to provide significant information for the study of the relationship between urinary iodine and thyroid node disease. Methods From January 2006 to December 2012, clinicopathologic data of 144 patients with thyroid carcinoma treated in the Beilun People＇s Hospital （our hospital for short） were retrospectively analyzed. The annual incidence cases, age, gender and household register, preoperative color ultrasound result, diseased parts, with pathological pattern or not, benign disease and lymphnode metastasis were recorded. Results The annual incidence cases were 8, 10, 10, 13, 23, 32 and 48 from 2006 to 2012 including 32 cases of male and 112 cases of female. The average onset age of male were （37.1±8.2） years old and the peak incidence age of male was 30-50 years old; the average onset age of female were （47.0±12.3） years old, and the peak incidence age of female was 25-55 years old. 120 cases （83.3%） of Beilun household register were found, 24 cases （16.7%） of ancestry were found, the differences were statistically significant （P = 0.02）. 120 cases of thyroid calcification were detected by color ultrasonic doppler before operation including 76 cases （52.8%） of mierocalcification. 134 cases （93.1%） of papillary thyroid carcinoma, 15 cases （10.4%） of follicular thyroid carcinoma and 1 case （0.7%） of medullary thyroid carcinoma were found, among which 6 eases of papillary thyroid carcinoma combined with follicular thyroid carcinoma at the same time were found. 80 （55.6%） cases were found at lobus dexter of thyroid, 36 （25.0%） cases were found at left lobe of thyroid, and 28 （19.4%） cases were found at two sides. 72 cases were detected with lymphnode metastasis, the rate of lymphnode metastasis of male and female patient were 62.5% and 46.4% respectively, and the difference was not statistically significant （P = 0.11）. The rate of lymphnode metastasis of age 〈
出处
《中国医药导报》
CAS
2013年第31期57-59,共3页
China Medical Herald
基金
浙江省医药卫生科技计划项目(编号2011KYB104)
关键词
甲状腺肿瘤
钙化
淋巴结转移
Thyroid carcinoma
Calcification
Lymphnode metastasis
